Abstract Modern car bodies are constantly relying higher proportions of high and ultra-high strength steels. In the past, increase in material strengths led to a conflict regarding complexity component geometries. Limits formability reached compromises had be made part design. By integrating application-oriented problems into development, these limits expanded with respect given requirements. W...

placement of narcotics inside intestinal tract of passengers and their illegal transfer through police stations and customs is called body packer or body bagger syndrome.in other parts of the world transfer of cocaine by this method has been reported.this prospective study was done with the help of Anti-narcotic Agency on the transfer of opium and heroin packages from Fenruary 1996 to January 1...

Higher operational efficiency of container transportation can be achieved by putting into operation hopper containers. The special feature a is its inclined end and sidewalls, which makes it possible to self-discharge bulk freight through the discharging hatches forming floor. vertical loading placed on long-base flat car was determined with mathematical modelling. model described translational...

The Home Office Police Research Group (PRG) was formed in 1992 to carry out and manage research relevant to the work of the police service and Home Office Policy Divisions. One of the major police department divisions which acts as customer for the PRG is the Home Office Crime Prevention Unit which was formed in 1983 to promote preventative action against crime. It has a particular responsibili...

conclusions the os trigonum syndrome should take in consideration in elderly subject who had posterior ankle pain starting after a car accident. case presentation a 62-year-old female patient was admitted with load depended ankle pain and swelling, lasting for five years which promptly started after a car accident. we incidentally discovered os trigonum on plain radiography on a lateral view of...

conclusion the chances of sustaining serious spine and associated multiple injuries in car accidents are quite high in iran. this may be due to the low level of standards or car manufacturing, absence, or inadequacy of appropriate safety measures in cars, poorly designed roads, and problems in the quality of driving to mention just a few reasons. therefore, these victims are prone to significan...

The manufacture of natural fiber composites was carried out to determine whether the composite from a combination palm and straw feasible as substitute for synthetic used electric car bodies at State Polytechnic Madura. This research conducted with variations in ratio 100% fiber, 1: 2, 2: 1 1. Testing material alloys by testing impact test, tensile on car’s body prototype. Based test results pr...

Novel immunotherapeutic agents targeting tumor-site microenvironment are revolutionizing cancer therapy. Chimeric antigen receptor (CAR)-engineered T cells are widely studied for cancer immunotherapy. CD19-specific CAR-T cells, tisagenlecleucel, have been recently approved for clinical application. Ongoing clinical trials are testing CAR designs directed at novel targets involved in hematologic...

The constitutive androstane receptor (CAR) transactivation can occur in the absence of exogenous ligand and this activity is enhanced by agonists TCPOBOP and meclizine. We use biophysical and cell-based assays to show that increased activity of CAR(TCPOBOP) relative to CAR(meclizine) corresponds to a higher affinity of CAR(TCPOBOP) for the steroid receptor coactivator-1. Additionally, steady-st...