Syzygium jambos (L.) Alstone belonging to the Myrtaceae family have been investigated for evaluation of their biological activities namely antioxidant and antimicrobial activity. The n-hexane, carbon tetrachloride, chloroform, aqueous soluble fractions of methanolic extract as well as crude methanolic extract of stem barks of Syzygium jambos were evaluated for their free radical scavenging acti...

In the present study, the hepatoprotective activity of ethanolic and aqueous extracts of Amorphophallus campanulatus (Roxb.) tubers were evaluated against carbon tetrachloride (CCl4) induced hepatic damage in rats. The extracts at a dose of 500 mg/kg were administered orally once daily. The substantially elevated serum enzymatic levels were significantly restored towards normalization by the ex...

A poly(vinyl alcohol) (PVA) membrane containing iron (Fe(0)) particles was developed and tested as a model barrier for contaminant containment. Carbon tetrachloride, copper (Cu2+), nitrobenzene, 4-nitroacetophenone, and chromate (Cr04(2-)) were selected as model contaminants. Compared with a pure PVA membrane, the Fe(0)/PVA membrane can increase the breakthrough lag time for Cu2+ and carbon tet...

BACKGROUND/AIMS We aimed to investigate the hepatoprotective effects of dihydromyrcenol and geranyl formate extracted from the Vitis vinifera L. plant in a rat model of acute hepatic injury induced by carbon tetrachloride. METHODS The study was performed on 54 Sprague-Dawley male rats. The animals were divided into 9 study groups with 6 rats in each. At the end of the 7-day study period, the ...

A method for determining chloroform, 1,1,1-trichloroethane, carbon tetrachloride, and trichloroethene in breath samples was developed. It consisted of collecting samples in 40-ml. glass-silanized tubes that were 16-in. long and had a 0.64-in. diameter. The ends tapered, resulting in a tube with a 1/4-in. diameter that was 1 3/4-in. long; each end had a shutoff valve attached. One end had a stri...

OBJECTIVE To estimate the hepatoprotective effects of the methanolic seed extract of Eugenia jambolana Lam. (Myrtaceae), in Wistar albino rats treated with carbon tetrachloride (CCl(4)). MATERIALS AND METHODS Liver damage in rats treated with CCl(4) (1ml/kg/Bw, administered subcutaneously, on alternate days for one week) was studied by assessing parameters such as serum glutamate oxaloacetate...

The mechanism by which the ingestion of carbon tetrachloride results in distinct and reproducible histological alterations of the liver has been investigated intensively, both in &JO and in vitro (3-11). The mitochondria of liver cells are particularly vulnerable to this lipid solvent, as shown by their increased permeability (3), decreased coenzyme content (7, 8), and the loss of their ability...

Buckwheat honey, which is widely consumed in China, has a characteristic dark color. The objective of this study was to investigate the protective effects of buckwheat honey on liver and DNA damage induced by carbon tetrachloride in mice. The results revealed that buckwheat honey had high total phenolic content, and rutin, hesperetin, and p-coumaric acid were the main phenolic compounds present...

The catalase activities in blood and organs of the acatalasemic (C3H/AnLCs(b)Cs(b)) mouse of C3H strain are lower than those of the normal (C3H/AnLCs (a)Cs(a)) mouse. We examined the effects of prior low-dose (0.5 Gy) X-ray irradiation, which reduced the oxidative damage under carbon tetrachloride-induced hepatopathy in the acatalasemic or normal mice. The acatalasemic mice showed a significant...

Houttuynia cordata Thunb (Saururaceae) is a traditional medicinal herb used to treat several disease symptoms. The present study was focused on the hepatoprotective effects of H. cordata ethyl acetate extract in experimental mice. Further the antioxidant potential of the extract was also evaluated to substantiate its hepatoprotective properties. Carbon tetrachloride-induced hepatic damage in mi...