intermediateand high-grade tumors; (iii) the term ‘tumor’ (neuroendocrine tumor, NET) is meant for lowto intermediate-grade neoplasms, as previously defined either ‘carcinoid’ or ‘atypical carcinoid’; (iv) the word ‘carcinoma’ (neuroendocrine carcinoma, NEC) is meant only for high-grade neoplasms, as previously defined poorly differentiated carcinomas. This terminology is adopted by the ENETS 2...

Carcinoid tumour is a rare entity accounting for less than two percent of bronchial neoplasms. They are rare welldifferentiated, neuro-endocrine tumors, with low-grade malignancy. They are distinguished in two different groups: typical and atypical carcinoid. Typical and atypical carcinoids differ in their biological behavior and prognosis. Atypical bronchial carcinoid tumor is still rare. We r...

The Authors report a case of tumour carcinoid of the appendix incidentally found at operation for appendicitis in a young patient. Diagnosis was confirmed at histologic analysis of the operating piece. Appendiceal carcinoid is the most frequent carcinoid tumor of the gastrointestinal tract and rarely becomes malignant. The Authors emphasize the importance of the knowledge of this not rare neopl...

We used T2-STIR (Short Tau Inversion Recovery) cardiovascular magnetic resonance to demonstrate carcinoid tumor metastases to the heart and liver in a 64-year-old woman with a biopsy-proven ileal carcinoid tumor who was referred because of an abnormal echocardiogram.

Institution: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. Clinical Hospital of the Medical School of University of São Paulo. São Paulo / SP – Brazil Address for correspondence: Flavio Akira Sakae – Rua Nanuque, 432 – Apto 102 – São Paulo / SP – Brazil – Zip code: 05302-031 – Fax: (+55 11) 3763-2715 – E-mail: [email protected] Article received on April 11,...

Molecular analysis of a metastatic lesion of an atypical carcinoid tumor of the lung obtained from a 77-year-old man at autopsy revealed a point mutation in the p53 gene and a deletion in the retinoblastoma (Rb) mRNA. This case suggests that both these antioncogenes may be involved in the progression of atypical carcinoid tumor.

1. Raslan WF, Ro JY, Ordonez NG, Amin MB, Troncoso P, Sella A, et al. Primary carcinoid of the kidney. Immunohistochemical and ultrastructural studies of five patients. Cancer. 1993;72: 2660–6. 2. Krishnan B, Truong LD, Saleh G, Sirbasku DM, Slavin KM. Horseshoe kidney is associated with an increased relative risk of primary renal carcinoid tumor. J Urol. 1997;157:2059–66. 3. Gross MI, Berger I...

Primary atypical carcinoid of the breast is rare. Herein we present a case of atypical carcinoid of the breast treated with surgery. The management plan is commented. Moreover an overview of the current evidence is presented. All the evidence is classified as level IV (opinion-based evidence) since there is no satisfactory case series to support a certain therapeutic decision. The treatment for...