The 4-ACGC isolated from BP was prepared to investigate the cardioprotective effects on attenuating chronic heart failure in vivo and in vitro. A chronic heart failure (CHF) rat model was established to investigate the cardioprotective effects of 4-ACGC. From this, several cardiac function indexes were recorded. The inflammatory markers including tumor necrosis factor-α (TNF-α), Interleukin-6 (...

Primary cardiac tumors are rare in children, with the prevalence of 0.0017–0.28% in autopsy series.[1] Benign tumors account for over 90% of the total. Cardiac fibromas (CFs) represent the second most common benign cardiac tumor in the pediatric population following rhabdomyomas. Patients can be asymptomatic or present with palpitations, cardiac murmur, arrhythmias, congestive heart failure, an...

Advanced cancer induces fundamental changes in metabolism and promotes cardiac atrophy and heart failure. We discovered systemic insulin deficiency in cachectic cancer patients. Similarly, mice with advanced B16F10 melanoma (B16F10-TM) or colon 26 carcinoma (C26-TM) displayed decreased systemic insulin associated with marked cardiac atrophy, metabolic impairment, and function. B16F10 and C26 tu...

Cardiac myxoma is most common among primary cardiac tumors, and its origin and tumor characteristics have been gradually elucidated by recent advances in molecular biology. Prichard's structure in the interatrial septum which was reported to be a candidate for the origin of cardiac myxoma, was revealed to be age-related changes. In hereditary cardiac myxoma "Carney complex", chromosomal abnorma...

BACKGROUND Cardiac Lipoma is a rare entity constituting approximately 10-19 % of primary tumors of the heart and pericardium. To our best knowledge, such a large cardiac lipoma with septal enhancement in our case has never been reported before. CASE PRESENTATION Here we present a rare case of a 65-year-old symptomatic female with an unusual giant cardiac lipoma. Due to the enhancement of the ...

conclusions pc-rplnd is one the major operations in the field of urology, which is associated with significant adjunctive surgeries. in appropriate cases, pc-rplnd was associated with good cancer specific survival in tertiary oncology center. results twenty-one patients underwent bilateral pc-rplnd. mean age was 26.3 years (ranged 16 - 47). mean size of retroperitoneal mass after chemotherapy w...

In order to review the surgical experience of a single institute with regard to the treatment of primary cardiac tumors, data was collected on patients with a histopathological diagnosis of a primary cardiac tumor (with the exception of myxoma) in a retrospective analysis of those treated between 2004 and 2013. In total, 11 patients were identified, with a mean age at diagnosis of 23 months and...

Cardiac metastases from bronchogenic carcinoma are not commonly diagnosed prior to death. This study isolates factors associated wtih the development of cardiac involvement. Four hundred eighteen consecutive patients with lung cancer who had autopsies were studied. Twenty-five percent of these patients had cardiac involvement. Factors associated with cardiac metastases were (1) histologic cell ...

OBJECTIVE Peripheral vascular surgery involving limb ischemia/reperfusion is associated with tumor necrosis factor-alpha production and an increased risk of cardiac complications. The objective of this study was to investigate the role of tumor necrosis factor-alpha in myocardial apoptosis and dysfunction following hindlimb ischemia/reperfusion. DESIGN Randomized perspective animal study. S...