CONTEXT A recent overview of all CVD models applicable to diabetes patients is not available. OBJECTIVE To review the primary prevention studies that focused on the development, validation and impact assessment of a cardiovascular risk model, scores or rules that can be applied to patients with type 2 diabetes. DESIGN Systematic review. DATA SOURCES Medline was searched from 1966 to 1 Apr...

Coronary heart disease and stroke contribute significantly to premature mortality and morbidity. Largely preventable, they demand prevention. Emphases range from responsibilities of governments to individuals, and the clinic nurses or doctors advising and treating them. The risk of cardiovascular disease varies. To be efficient and effective, medical interventions must focus on those at highest...

BACKGROUND The General Cardiovascular Risk Profile is a multivariable model that predicts global cardiovascular disease risk. Our goal was to assess the ability of the General Cardiovascular Risk Profile to identify individuals with advanced coronary artery calcification (CAC) and determine whether identification is improved with family history. METHODS AND RESULTS Using data from the Multiet...

BACKGROUND Screening tools to identify persons with high cardiovascular risk exist, but less is known about their validity in different population groups. The aim of this article is to compare the sensitivity and specificity of three different cardiovascular disease risk scores and their ability to detect high-risk individuals in daily practice. METHODS The sensitivity and specificity of risk...

Propensity scores have been used to reduce bias in observational studies in many fields and are becoming more widely used in cardiovascular research.1 The goal of this statistical primer is to present the definition of propensity scores and to illustrate their use by describing some recent examples found in the cardiovascular disease research literature. Large-scale epidemiological cohort studi...

Others have analysed the relationship between inadequate behaviour by healthcare professionals in the diagnosis of dyslipidaemia (diagnostic inertia) and the history of cardiovascular risk factors. However, since no study has assessed cardiovascular risk scores as associated factors, we carried out a study to quantify diagnostic inertia in dyslipidaemia and to determine if cardiovascular risk s...

OBJECTIVE To develop a strategy for stratifying risk of cardiovascular disease (CVD) in a cohort of patients with SLE and to test the usefulness of this strategy in rationalizing management of cardiovascular risk factors. METHODS For each patient, data were collected once each year to allow calculation of risk of developing CVD in the next 10 years. Those with risk values >7.5% were considere...