BACKGROUND AND PURPOSE Large pulse pressure associates with atherosclerosis, but it is unclear if it contributes to the development of atherosclerosis or if atherosclerosis leads to pulse pressure widening. We examined whether exposure to large pulse pressure in childhood predicts carotid artery intima-media thickness in adulthood. METHODS Carotid intima-media thickness was measured in 2146 a...

BACKGROUND AND PURPOSE The recent increase in clinical cardiovascular disease in Alaska Eskimos suggests that changes in traditional lifestyle may have adverse public health consequences. This study examines the prevalence of subclinical vascular disease and its relation to risk factors in Alaska Eskimos. METHODS Participants in the population-based Genetics of Coronary Artery Disease in Alas...

vertebrobasilar insufficiency is the cause of cerebrovascular accidents in 20% of cases. there are few reports regarding spectral doppler indices (sdis) of vertebral arteries (vas) normal blood flow. the objective of this study was to provide basic reference data about sdis of vas normal blood flow separately and in comparison with internal carotid arteries (icas) and common carotid arteries (c...

BACKGROUND AND PURPOSE Calcified arterial plaque has been proposed as a subclinical marker of atherosclerosis. We compared it to a well-validated surrogate--carotid intimal medial thickness (IMT). METHODS Calcified arterial plaque was measured in 2 vascular beds (coronary and carotid) by computed tomography, and common carotid artery IMT was measured by B-mode ultrasonography, in 438 particip...

BACKGROUND An elevated level of homocysteine (Hcy) in the blood is designated hyperhomocysteinaemia (Hhcy) and is regarded as a strong risk factor for the development of atherosclerosis (ATH), although the association remains controversial. Considered to be essential gene expression regulators, micro-RNAs (miRNAs) modulate cardiovascular disease development and thus can be regarded as potential...

OBJECTIVE Comprehension of the pathophysiologic characteristics of atherosclerosis has focused its attention on the study of dynamic and metabolic processes involving the vessel wall as possible causes of stroke. When compared with conventional radiologic techniques, sonography has the main advantage of being a real-time imaging modality. We report 2 acute stroke cases in which carotid sonograp...

Högberg, D. 2017. Screening for asymptomatic carotid atherosclerosis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1367. 77 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0060-3. Ischemic stroke is the most common cause of handicap in adults and the third most common cause of death in Sweden. Internal carotid artery atherosclerosis is an im...

BACKGROUND Few studies have reported on the relationship between metabolic syndrome (MetS) and carotid artery structure. The objective of this study was to examine the relationship between MetS and carotid artery parameters such as the common carotid artery intima-media thickness (CCA-IMT), plaques, and the diameter of the common carotid artery (CCAd). METHODS AND RESULTS The study population...

Introduction: Carotid atherosclerosis is one of the main causes ischaemic stroke. The study verified hypothesis on relationship between expression selected inflammatory markers and stability atherosclerotic plaque in stroke patients. Aim: aim was to determine CCL3 CCL5 levels both plasma carotid plaques relation history stroke, as well assess morphology stability. Materials methods: chemokines ...

OBJECTIVES We aimed to define the relationship between cerebral atherosclerosis and stroke after coronary artery bypass grafting (CABG). BACKGROUND Although cerebral atherosclerosis may play a crucial role in the advent of post-CABG stroke, only extracranial carotid artery disease has been extensively studied, and the effects of atherosclerosis on the mechanisms underlying post-CABG stroke re...