The Period 3 and Clock genes are important components of the mammalian molecular circadian system. Studies have shown association between polymorphisms in these clock genes and circadian phenotypes in different populations. Nevertheless, differences in the pattern of allele frequency and genotyping distribution are systematically observed in studies with different ethnic groups. To investigate ...

INTRODUCTION In the phase IV, open-label, single-arm study NCT01203917, first-line gefitinib 250 mg/d was effective and well tolerated in Caucasian patients with epidermal growth factor receptor (EGFR) mutation-positive non-small-cell lung cancer (previously published). Here, we report EGFR mutation analyses of plasma-derived, circulating-free tumor DNA. METHODS Mandatory tumor and duplicate ...

Objective: The objective was to document the effects late-summer prescribed fire on soil cover, botanical composition, and forage production in Kansas Smoky Hills associated dense Caucasian bluestem (Bothriochloa bladhii) stands therein.

Hip and vertebral fractures are a public health problem in men of Asian and Caucasian origin. Inferences regarding gender and racial/ethnic differences in fracture rates must be made cautiously as problems in case ascertainment and classification of hip fractures, and problems in defining what constitutes a vertebral 'fracture' have not been solved. However, methodological issues probably do no...

We present a patient with the picture of corneal white spots, very similar in morphology to those described in native West Indians, occurring here in a Caucasian. Their aetiology remains obscure.

study due to chronic anemia. The microscopical study exhibited a malignant tumor composed of two different epithelial cell types (Fig. 1), with an infiltrating growth pattern, and wide necrotic and hemorrhage areas. Nearly 60% of the tumor was an atypical polygonal cell proliferation with intercellular bridges, keratin, and presence of pearl corns (Fig. 2), which was a squamous carcinoma. The r...

The South Caspian Basin (SCB) is the deepest submerged sedimentary basin in World and occupies entire southern deep-water part of Sea Kura West Turkmenian lowlands adjacent to it from west east. SCB has thinnest (6...8 km) consolidated oceanic-type crust thickest cover (25...30 km). thickness Pliocene-Quaternary deposits 10...12 km. main oil gas complex – Productive-Red-Colored Strata Lower Pli...

Classical anatomical teaching reports the presence of the lateral palpebral raphe formed at the union in the preseptal and orbital parts of the orbicularis oculi muscle, or by the tendon adhering these to the underlying zygomatic bone. The lateral palpebral raphe has been shown to be absent in Asian cadavers. The current study uses both evidence from the anatomical dissection of five eyelids fr...