The computational design of materials with ionic bonds poses a critical challenge to thermodynamic modeling since density functional theory yields inaccurate predictions their formation enthalpies. Progress requires leveraging physically insightful correction methods. recently introduced coordination corrected enthalpies (CCE) method delivers accurate mean absolute errors close room temperature...

Yadin David, EdD, PE, CCE, Matthew Baretich, PE PhD, William A. Hyman, PE, ScD, Wayne Morse, and James O. Wear, MSBME, CCE, FACCE From the Biomedical Engineering Consultants, LLC, Houston, Texas (Dr David); Baretich Engineering, Inc, Fort Collins, Colorado (Dr Baretich); Department of Biomedical Engineering, Texas A&M University, College Station (Dr Hyman); Morse Medical, Linc Facility Services...

Critical Care Echocardiography (CCE) was introduced into intensive care medicine practice several decades ago and is now established as a mainstream technique. It is widely used for the diagnosis, monitoring and management of the critically ill patient. Evolving experience and research in CCE has justified its role in the diagnosis of undifferentiated shock, management of the difficult post car...

Hypoxic pulmonary vasoconstriction (HPV) requires influx of extracellular Ca2+ in pulmonary arterial smooth muscle cells (PASMCs). To determine whether capacitative Ca2+ entry (CCE) through store-operated Ca2+ channels (SOCCs) contributes to this influx, we used fluorescent microscopy and the Ca2+-sensitive dye fura-2 to measure effects of 4% O2 on intracellular [Ca2+] ([Ca2+]i) and CCE in prim...

INTRODUCTION Sleep is a complex phenomenon characterized by important modifications throughout life and by changes of autonomic cardiovascular control. Aging is associated with a reduction of the overall heart rate variability (HRV) and a decrease of complexity of autonomic cardiac regulation. The aim of our study was to evaluate the HRV complexity using two entropy-derived measures, Shannon En...

We examined capacitative calcium entry (CCE) in Jurkat and in L6 skeletal muscle cells. We found that extracellular Ca2+ can enter the endoplasmic reticulum (ER) of both cell types even in the presence of thapsigargin, which blocks entry into the ER from the cytosol through the CaATPase. Moreover, extracellular Ca2+ entry into the ER was evident even when intracellular flow of Ca2+ was in the d...

Sweeney, Michele, Ying Yu, Oleksandr Platoshyn, Shen Zhang, Sharon S. McDaniel, and Jason X.-J. Yuan. Inhibition of endogenous TRP1 decreases capacitative Ca2 entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 283: L144–L155, 2002. First published February 8, 2002; 10.1152/ ajplung.00412.2001.—Pulmonary vascular medial hypertrophy due to p...

Following smooth muscle excitation and contraction, depletion of intracellular Ca(2+) stores activates capacitative Ca(2+) entry (CCE) to replenish stores and sustain cytoplasmic Ca(2+) (Ca(2+)(i)) elevations. The objectives of the present study were to characterize CCE and the Ca(2+)(i) dynamics underlying human colonic smooth muscle contraction by using tension recordings, fluorescent Ca(2+)-...

Efficient use of seed nutrient reserves is crucial for germination and establishment of plant seedlings. Mobilizing seed oil reserves in Arabidopsis involves β-oxidation, the glyoxylate cycle, and gluconeogenesis, which provide essential energy and the carbon skeletons needed to sustain seedling growth until photoautotrophy is acquired. We demonstrated that H(+)-PPase activity is required for g...