نتایج جستجو برای: cell signalling

تعداد نتایج: 1710297  

Journal: :Annals of the Rheumatic Diseases 2023

Background Anti-citrullinated protein antibodies (ACPA) play a role in rheumatoid arthritis (RA) pathogenesis, and their presence is associated with disease severity. Moreover, high serum levels of ACPA the preclinical phase are one major risk factors for RA progression. Consequently, detailed analysis pos B cells required to disentangle these RA. Multiple intracellular signalling pathways invo...

The yeast strains that are resistant to high concentration of ethanol have biotechnological benefits and aresuitable models for physiology and molecular genetics research fields. A novel ethanol-tolerant mutant strain,mut1, derived from the commercial Saccharomyces cerevisiae showed higher ethanol production, and alsodemonstrated resistance to ethanol but not to other alcohols...

Journal: :Biochemical Society Transactions 2018

Journal: :Pakistan biomedical journal 2022

A small number of signalling pathways, including receptor tyrosine kinases (RTKs) and G protein-coupled receptors (GPCRs), are activated by plasma membrane in order for cells to respond external cues. In addition transmitting, these pathways also process, encode, integrate both internal signals. recent years, it has become clear that different spatio-temporal activation profiles the same set pr...

Journal: :Journal of cell science 2015
Viesturs Simanis

The septation initiation network (SIN) regulates aspects of cell growth and division in Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results in improper assembly of the contractile ring and failure of cytokinesis, generating multinucleated cells, whereas too much SIN signalling uncouples cytokinesis from the rest of the cell cycle. SIN signalling is theref...

Journal: :Development 2010
Mai Yamamoto Ryoko Morita Takamasa Mizoguchi Hiromi Matsuo Miho Isoda Tohru Ishitani Ajay B Chitnis Kunihiro Matsumoto J Gage Crump Katsuto Hozumi Shigenobu Yonemura Koichi Kawakami Motoyuki Itoh

In the developing embryo, cell-cell signalling is necessary for tissue patterning and structural organization. During midline development, the notochord plays roles in the patterning of its surrounding tissues while forming the axial structure; however, how these patterning and structural roles are coordinated remains elusive. Here, we identify a mechanism by which Notch signalling regulates th...

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