نتایج جستجو برای: cellular defence system

تعداد نتایج: 2600804  

Journal: :Metallomics : integrated biometal science 2016
Clara Shen Jacek L Kolanowski Carmen M-N Tran Amandeep Kaur Mia C Akerfeldt Matthew S Rahme Trevor W Hambley Elizabeth J New

Copper plays a key role in the modulation of cellular function, defence, and growth. Here we present InCCu1, a ratiometric fluorescent sensor for mitochondrial copper, which changes from red to blue emission in the presence of Cu(i). Employing this probe in microscopy and flow cytometry, we show that cisplatin-treated cells have an impaired ability to accumulate copper in the mitochondria.

Journal: :Immunology today 1998
E Meinl H Fickenscher M Thome J Tschopp B Fleckenstein

Induction of apoptosis of virus-infected cells is an important host cell defence mechanism. However, some viruses have incorporated genes that encode anti-apoptotic proteins or modulate the expression of cellular regulators of apoptosis. Here, Edgar Meinl and colleagues discuss recent evidence that viral interference with host cell apoptosis leads to enhanced viral replication, and to evasion o...

Journal: :International Journal of Production Economics 2017

Journal: :Canadian Journal of Anesthesia/Journal canadien d'anesthésie 1999

2014
Xianyang Chen Hexigeduleng Bao Jie Guo Weitao Jia Fang Tai Lingling Nie Ping Jiang Juanjuan Feng Sulian Lv Yinxin Li

Despite the importance of NHX1 (Na(+)/H(+) exchanger 1) in plant salt tolerance, little is known about its other functions. In this study, intriguingly, it was found that NHX1 participated in plant disease defence against Phytophthora parasitica var. nicotianae (Ppn) in Nicotiana benthamiana. NbNHX1 was originally isolated from N. benthamiana, and characterized. The subcellular localization of ...

Journal: :Current Biology 1999
Lloyd W Ruddock Peter Klappa

A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environmental redox potential. This provides a rapid first defence mechanism against the potentially very harmful toxic effects of oxidative stress.

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