The work is devoted to a study of the microstructure and microhardness heat-resistant nickel-based superalloy 58Ni-Cr-Mo-B-Al-Cu after radial-shear rolling. rolling was carried out at temperature 925°С in three stages. It found that grain size γ-phase all stages decreased radial direction from center periphery 62 ± 2 2.5 0.2 µm. At third stage, grains reduced twice billet comparison initial sta...

Lee et al. report that an angiotensin II type 1 receptor blocker (ARB) improved glucose intolerance in OLETF rats, an experimental model of type 2 diabetes. ARB treatment resulted in modulation of the adipose tissue, leading to an increased number of small, differentiated adipocytes able to produce more adiponectin and less monocyte chemoattractant protein-1 and plasminogen activator inhibitor-...

Near infrared imaging (NIR) camera systems have been clinically deployed to visualize intravenous injected indocyanine green (ICG) spreading through the vascular bed, thereby creating ability assess tissue perfusion. While standardization is key make fluorescence angiography (FA) comparable and reproducible, optical characteristics like field illumination homogeneity are often not considered. T...

We study a model of network formation where the bene…ts from connections exhibit decreasing returns and decay with network distance. We show that the unique equilibrium network is a periphery-sponsored star, where one player, the center, maintains no links and earns a high payo¤, while all other players maintain a single link to the center and earn lower payo¤s. Both the star architecture and p...

The case of urban development in the Russian periphery is often overlooked scholarly efforts to theorize center-periphery dynamics characteristic post-socialist contexts, not least Russia. Consequently, analysis initiatives regions and provinces defies logic large-scale projects with subdominant relations between state private sector, since latter former are tied competition for limited federal...

The compartmental organization of eukaryotic cells is maintained dynamically by vesicular trafficking. SNARE proteins play a crucial role in intracellular membrane fusion and need to be targeted to their proper donor or acceptor membrane. The molecular mechanisms that allow for the secretory vesicles carrying the v-SNARE TI-VAMP/VAMP7 to leave the cell center, load onto microtubules, and reach ...

Our everyday interaction in and with the physical world, has facilitated the development of auditory perception skills that enable us to selectively place one auditory channel in the center of our attention and simultaneously monitor others in the periphery. We search for ways to leverage these auditory perception skills in interactive systems. In this paper, we present three working demonstrat...

Cerebral cortical ischemia was induced in anesthetized rats by occlusion of the middle cerebral artery (MCA). Cerebral blood flow (CBF) was measured with the H2 clearance technique in the center and periphery of the ischemic territory. A decrease of CBF to about 50% of pre-occlusion values was observed in both areas. Administration of Physostigmine, a cholinesterase inhibitor, at a dose of 0.15...