This paper introduces a new technique for identifying composite design patterns from existing patternbased designs. We propose two pattern metrics: pattern coverage and overlapping that can help detect a composite pattern. The effective composite patterns reflect quality properties that are considered desirable in the solution for a given problem domain and selected programming paradigm. To ide...

In the present investigation, we report that statistical design and optimization of significant variables for the microbial production of citric acid from sucrose in presence of filamentous fungi A. niger NCIM 705. Various combinations of experiments were designed with Central Composite Design (CCD) of Response Surface Methodology (RSM) for the production of citric acid as a function of six var...

The enantiomeric separation of some nonsteroidal antiinflammatory drugs was investigated on an avidin column. An experimental design approach (central composite design) was used to evaluate the effects of three method parameters (pH, concentration of organic modifier, and buffer concentration) on the analysis time and the resolution, as well as to model these responses. This revealed that the o...

Arsenic is a highly toxic element for human beings, which is generally found in groundwater. Dissolved Arsenic in water can be seen as As+3 and As+5 states. The adsorption process is one of the available methods to remove Arsenic from aqueous solutions. Thus, this papers aims at removing Arsenic (III) from aqueous solutions through adsorption on iron oxide granules. The relation among four inde...

the aim of this research was to optimize bioremediation of seawater samples spiked with 1000 mg/l crude oil for removal of n-alkanes (c12h26 to c34h70). bioaugmentation experiments were performed at laboratory scale: each bioreactor contained 250 ml dispersed crude-oil-contaminated seawater, indigenous acclimatized microorganism and nitrogen and phosphorus at concentrations based on central com...

In this work, a novel and modified method for the solvent purification of Curcumin is presented, a composite of normal hexane & 2-propanol solvents was used to separate the fat content and other impurities. The process was modeled considering the response surface methodology as described by the central composite design. The adjusted R-squared was 0.9443 indicating the variation betwe...

Thermal cracking of a heavy liquid hydrocarbon was performed in a laboratory scale tubular reactor. Central Composite Design (CCD), was used as an experimental design method. The design variables were Coil Outlet Temperature (COT), feed flow and rate steam ratio. Maximum yield of ethylene was 30.37 wt% at COT, residence time and steam ratio of 869oC, 0.208 s and 1.22 g/g, respect...

the objective of this study was to produce fish protein hydrolysate (fph) with the most antioxidant activity, by enzymatic hydrolysis from (carassius carassius). the protein of crucian carp a low value fish was hydrolyzed by alcalase 2.4l and the optimal hydrolysis parameters of strongest antioxidant capacity of peptides were obtained using response surface methodology (rsm) by the central rota...