OBJECTIVE Girls with precocious puberty have high luteinizing hormone (LH) levels and advanced bone age. Obese children enter puberty at earlier ages than do non-obese children. We analyzed the effects of obesity on LH secretion during gonadotropin-releasing hormone (GnRH) tests in girls with precocious puberty. METHODS A total of 981 subjects with idiopathic precocious puberty who had underg...

The objectives of this study were to determine the incidence of precocious puberty and effect of exposure to a bull on the incidence of precocious puberty in beef heifers. The experiment was conducted using 120 heifers during 1990 and 1991. Heifer calves were randomly assigned to be pastured in the presence (n = 30 heifers/yr) or absence (n = 30 heifers/yr) of a bull starting at 140 +/- 14 d of...

OBJECTIVE Precocious puberty leads to discrepancies between physical and chronological age. The aim of the present study was to evaluate behavioral patterns and social competences in 34 girls with idiopathic precocious puberty. METHODS Height, body weight, and BMI were determined, and pubertal development was assessed. The Korean-child behavior checklist (K-CBCL) was completed by parents. R...

Evaluation of the sellar area was performed with magnetic resonance imaging in 101 patients (age range 0.8-27 years) with hypopituitarism, isolated diabetes insipidus, hypogonadotrophic hypogonadism, and central precocious puberty. The hypopituitary patients (n = 70) included multiple pituitary deficiency (n = 23), pituitary deficiency with diabetes insipidus (n = 5), and isolated growth hormon...

  A 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. On physical examination café au lait macular spots were noted on her neck, buttocks and left leg. Bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. Considering the presence of polyostotic fibrous...

OBJECTIVE Bisphenol A (BPA) is an industrial chemical, particularly used to harden plastics. BPA is thought to have negative health effects on both laboratory animals and humans. Consider ing the decline in age of onset of puberty noted in recent years, particularly among girls, the importance of BPA as an estrogenic endocrine disruptor has increased. In this study, we aimed to determine urinar...

a 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. on physical examination café au lait macular spots were noted on her neck, buttocks and left leg. bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. considering the presence of polyostotic fibrous dysplasia, precocious pubert...

BACKGROUND Central precocious puberty (CPP) and phenylketonuria (PKU) are two rare conditions, the latter being the rarer. To date, only one case featuring both these conditions has been reported, and hyperphenylalaninemia was assumed triggering CPP. CASE PRESENTATION We present a 3.2 years old girl referred with a 12 months history of breast and pubic hair development, and vaginal discharge....