Transcatheter aortic valve replacement (TAVR) has become a first-line treatment for severe stenosis with intermediate to high-risk population its use increasingly expanding into younger and low-risk cohorts as well. Cerebrovascular events are one of the most serious consequential complications TAVR, which increase morbidity mortality. The probable origin such neurological is embolic in nature m...

Resistance breathing improves tolerance to central hypovolemia induced by lower body negative pressure (LBNP), but this is not related to protection of anterior cerebral blood flow [indexed by mean middle cerebral artery velocity (MCAv)]. We hypothesized that inspiratory resistance breathing improves tolerance to central hypovolemia by maintaining cerebral oxygenation (ScO2), and protecting cer...