THIS contribution consists in a review of work done during the severe epidemic of cerebro-spinal meningitis which occurred in Belfast during 1907 and 1908, together with some additional observations that have been made in France during the Great War and also during the present year in Belfast. During 1907 and 1908 we devised an application of Sir A. E. Wright's opsonic technique for the laborat...

Pte. J. W., cet. 24, ljftely admitted to hospital for " Paralysis agitans," presents marked symptoms of that rare affection ?Disseminated sclerosis. The disease appears to have supervened on a prolonged attack of secondary syphilis two years ago. His medical history sheet records several recent admissions for "ague" and "simple continued fever" which, according to the man's own statement, were ...

so persistent as in the tubercular form), suddenness of onset, then convulsive seizures and tonic spasms, much intolerance of being examined or handled, even when coma is beginning. The most striking clinical symptom is tonic spasm of the nuchal mv scles, with retraction of head, which cannot be replaced without great pain. Later, when effusion becomes established, and there is coma and Kernig'...

We investigated the MR appearance and incidence of low-signal areas within the CSF of the spinal canal. Nonuniform areas of decreased signal intensity in intracranial CSF have been named the CSF flow-void sign (CFVS) and appear to be due to spin dephasing secondary to pulsatile CSF motion. Similar areas are seen in the spinal canal. The MR scans of 50 randomly selected patients, constituting a ...

Throughout vertebrates, cerebrospinal fluid-contacting neurons (CSF-cNs) are ciliated cells surrounding the central canal in the ventral spinal cord. Their contribution to modulate locomotion remains undetermined. Recently, we have shown CSF-cNs modulate locomotion by directly projecting onto the locomotor central pattern generators (CPGs), but the sensory modality these cells convey to spinal ...

Spontaneous intracranial hypotension (SIH) caused by spontaneous spinal cerebrospinal fluid (CSF) leaks produces orthostatic headaches. Although upper arm pain or paresthesia is reportedly associated with SIH from spontaneous spinal CSF leak in the presence of orthostatic headache, low thoracic radicular pain due to spontaneous spinal CSF leak unassociated with postural headache is extremely ra...

Neurons in contact with the cerebrospinal fluid (CSF) are found around medullo-spinal central canal (CC) adult mice. These neurons (CSF-cNs), located within or below ependymal cell layer, known as stem niche, present a characteristic morphology dendrite projecting to CC and ending protrusion. They GABAergic, an intermediate neuronal maturity selectively express PKD2L1, member of transient recep...

We would like to propose floating dural sac sign, which is observed as a hyperintense band or rim around the spinal dural sac on axial T2-weighted images, as a sensitive sign to identify cerebrospinal fluid (CSF) leakage. One hundred patients with orthostatic headache were prospectively registered in 11 hospitals. These patients were examined by brain magnetic resonance (MR) imaging (n = 89), r...

come a time when the lecturer of the day will not have known him personally, hence it is the more a pious charge on those who have had the advantage of his friendship to commemorate his virtues. For they know well that Edward Long Fox was a man held in especial honour and affection by his medical brethren in this city and neighbourhood. Honoured for his wide culture and knowledge of his profess...