Meningitis is one of the most common infectious cerebral nervous system (CNS), defined as an inflammation of the meninges. It is clinically categorized into a chronic and acute based on the acuity of symptoms. Vomiting, bulging fontanel and fever are the main symptoms in the patients with meningitis. Bacterial meningitis is a severe, potentially life-threatening infection that is associated wit...

Beta2-Microglobulin ( β 2-m) is a low molecular weight protein occurring in all body fluids. Its concentration increases in various pathologies. Increased values in cerebrospinal fluid (CSF) are ascribed to an activation of immune system. Using immunoturbidimetry, we examined concentrations of beta2-microglobulin in cerebrospinal fluid in a large group of 6274 patients with defined neurological...

OBJECTIVE Cerebrospinal fluid (CSF) leaks may present as rhinorrhea or otorrhea and can lead to life-threatening complications if not detected. The usefulness of the morpholinopropanesulfonic acid (MOPS)-histidine buffer in detecting β₂-transferrin, which is only found in the cerebrospinal fluid, was compared with the standard barbital buffer. METHODS We evaluated 20 aural or nasal patient sp...

S100B in cerebrospinal fluid (CSF-S100B) was measured in calves with 20 neurologic and 21 non-neurologic diseases to clarify its utility as a biomarker for neurologic diseases. The median CSF-S100B value in the neurologic disease group (43.0 ng/ml) was significantly higher than that in the non-neurologic disease group (10.2 ng/ml). As CSF-S100B levels in calves with neurologic diseases widely d...

S100B in cerebrospinal fluid (CSF-S100B) was measured in calves with 20 neurologic and 21 non-neurologic diseases to clarify its utility as a biomarker for neurologic diseases. The median CSF-S100B value in the neurologic disease group (43.0 ng/ml) was significantly higher than that in the non-neurologic disease group (10.2 ng/ml). As CSF-S100B levels in calves with neurologic diseases widely d...

Detection of Mycobacterium tuberculosis complex (MTBC) in extrapulmonary specimens can be challenging due to their paucibacillary nature. This difficulty is especially true for cerebrospinal fluid (CSF), and the low sensitivity specificity diagnosis hampers rapid detection treatment vulnerable populations. GeneXpert MTB/RIF Ultra has been shown provide results MTBC associated Rifampin resistanc...

After neural tube closure, amniotic fluid (AF) captured inside the neural tube forms the nascent cerebrospinal fluid (CSF). Neuroepithelial stem cells contact CSF-filled ventricles, proliferate, and differentiate to form the mammalian brain, while neurogenic placodes, which generate cranial sensory neurons, remain in contact with the AF. Using in vivo ultrasound imaging, we quantified the expan...

Spontaneous intracranial hypotension (SIH) is a condition in which the fluid pressure inside skull lower than normal. It secondary to cerebrospinal (CSF) leak at level of spine and resulting loss CSF volume. Pseudo-subarachnoidal hemorrhage rare that can occur patients with spontaneous hypotension. The diagnosis very important because it be confused true subarachnoidal hemorrhage. True one comp...

The concentration of cerebrospinal fluid total protein (CSF-TP) is important for the diagnosis neurological emergencies. Recently, some Western studies have shown that current upper reference limit CSF-TP quite low older patients. However, little reported about in Asian population. In this study, we retrospectively analyzed concentrations healthy Japanese volunteers. CSF samples 69 volunteers (...

26 J Kor Neurotraumatol Soc Cerebrospinal fluid (CSF) rhinorrhea involves a breakdown of all barriers that separate the subarachnoid space from the upper aerodigestive tract, namely, the mucosa of the nasal cavity or paranasal sinus, skull base, dura mater, and arachnoid membrane. CSF rhinorrhea expressed as meningitis, subdural empyema or brain abscess, when inadequately treated 3,19) . CSF fi...