Introduction:Most metastatic lymph nodes from head and neck malignancy are solid. Cystic nodes are found in 33% - 61% of carcinomas arise from Waldeyer’s ring, of which only 1.8% - 8% originate are from the nasopharynx. Some cystic cervical metastases were initially presumed to be branchial cleft cyst. This case report aims to highlight the unusual presentation of cystic cervical metastasis sec...

We have routinely performed ultrasonography as the first-choice examination of neck masses since 1985. At the Department of Head and Neck Surgery, Kanagawa Cancer Center, the percentage of patients with head and neck cancer and neck masses is very high, and cervical ultrasonography is performed on more than 1,000 patients per year, including referrals from other departments. In patients with he...

OBJECTIVE To assess the feasibility of optical imaging using activatable near-infrared fluorescence (NIRF) agents to detect oral cancer and cervical lymph node metastasis in vivo. DESIGN In vivo study. SETTING University medical center. SUBJECTS Female nude mice aged 4 to 6 weeks. INTERVENTION Luciferase-expressing OSC-19-luc cells were injected into the tongues of nude mice. A control ...

Currently, somatic cell count (SCC) and bacterial culture are considered as the gold standard of detecting subclinical Mastitis. Mastitis leads to proliferation of lymphocytes in the supramammary lymph nodes and subsequent enlargement of ipsilateral lymph node. Ultrasonography can be used to survey these changes. A portable ultrasound machine with a 2-5 MHz convex transducer was used to identif...

To analyze Survivin, MMP-2, and MMP-9 expression in different types of cervical lesions and discuss their correlation and clinical significance. Patients with chronic cervicitis, cervical intraepithelial neoplasia, or cervical cancer in our hospital were collected. ELISA was applied to detect the level of Survivin, MMP-2 and MMP-9 in serum. Immunohistochemistry was used to measure Survivin, MMP...

PURPOSE The purpose was to test whether patient's primary malignancy type and presence of F-18-fluorodeoxyglucose (FDG)-avid cervical lymph node(s) are predictors of pathologic outcome of incidental focal FDG-avid parotid lesions. BASIC PROCEDURES A retrospective cohort study of pathologically proven incidental cases was performed. MAIN FINDINGS Focal parotid FDG uptake in the setting of he...

UNLABELLED Lymph node metastasis is the major clinicopathologic feature associated with poor prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Here, web-based bioinformatics meta-analysis was performed to elucidate the molecular mechanism of lymph node metastasis of human HNSCC. Preferential upregulation of Myosin 1b (MYO1B) transcript in HNSCC datasets was identified. M...

BACKGROUND USPIO is a contrast agent for MRI that can generate T2W images with low signal intensities. After subcutaneous or intravenous injection of USPIO, normal lymph node tissues uptake these nano-particles, but tumor cells do not. Thus, tumor metastasis can be detected using this contrast agent. OBJECTIVE The aim of this study was to access the feasibility of USPIO enhanced MRI for the d...

Lymph node metastasis is the single, most powerful prognostic factor in head and neck squamous cell cancer, which means that cervical lymph management should be considered even treatment of a clinically node-negative neck. More conservative selective techniques dissection have been developed ever since radical was first introduced. Despite provides less functional damage, disfiguring scar after...