Most traditional anticancer medications are ineffective in treating triple negative breast cancer (TNBC), which has enhanced resistance to chemotherapeutic agents. Herbs continue be a key element the discovery of medications. In present study, we assessed cytotoxicity methanol extract leaves Pergularia daemia (MLPD) MDA-MB-231 triple-negative (TNBC) cell line. The MLPD was using MTT assay revea...

BACKGROUND Cholangiocarcinoma (CCA) is highly resistant to most of the known chemotherapeutic treatments. NAD(P)H-quinone oxidoreductase 1 (NQO1) is an antioxidant/detoxifying enzyme recently recognized as an important contributor to chemoresistance in some human cancers. However, the contribution of NQO1 to chemotherapy resistance in CCA is unknown. METHODS Two CCA cell lines, KKU-100 and KK...

A major challenge in osteosarcoma (OS) is the selection of the most effective chemotherapeutic agents for individual patients, while the administration of ineffective chemotherapy increases mortality and decreases quality of life in patients. This emphasizes the need to evaluate every patient's probability of responding to each chemotherapeutic agent. We developed a profiling strategy for serum...

IMPORTANCE Several chemotherapeutic agents have been reported to induce subacute cutaneous lupus erythematosus (SCLE). To our knowledge, this is the first report to date of SCLE induced by monotherapeutic gemcitabine hydrochloride and includes a comprehensive review of all published cases of chemotherapeutic drug-induced SCLE. OBSERVATIONS We describe a patient who developed a SCLE-like erupt...

right of private property is of the most important individual rights of society that lies in the heart of private law. in islamic law protection of property as one of the five goals of fighhe, that is, protection of sagacity, religion, generation and self, is to be stipulated. based on article 140 of civil code the process of property acquisition is restricted to four cases. on the other hand, ...

Because some antibiotics have proved active in certain parasitic infections, there appears to be good prospect that this rapidly growing and meagerly tested class of chemotherapeutic agents (there are already some 4,000 known antibiotics!) will some day provide efficient treatments for some of the parasitic diseases of livestock and poultry. Antibiotics are especially useful for combating bacte...

A set C can be strongly coded under condition < B, C(A) >, where B and C are classes of sets possibly with other parameters, iff there exists A ∈ B such that every Z ∈ C(A) can be used to compute C. The issue is widely studied especially in effective mathematics and reverse mathematics. In this paper, we focus on three kinds of conditions, namely, density condition, enumeration condition and pa...

Red rice contains pharmacological substances including phenolics, oryzanol, tocotrienol and tocopherol. Recently, red rice extract has been employed as a source of antioxidants for inhibition of tumor growth. This study was carried out to evaluate the anti-invasion effects of red rice extract fractions on cancer cells. It was found that at 100 μg/ml of crude ethanolic extract (CEE), hexane frac...