We propose and studied optical coherence tomography (OCT) combining spectroscopic (SOCT) and speckle variance (svOCT) functions to effectively detect locations of microvasculatures and assess blood oxygen saturation level. Chorioallantoic membrane of a chick embryo was imaged in vivo to perform the analysis of the system. We also studied the effect of speckle in spectral domain using experiment...

Resveratrol is a polyphenolic compound which found in many nutrients including grapes, peanuts, raspberries, and apples. Anti-proliferative, anti-angiogenic apoptotic effects of resveratrol have been shown on various cancer cells. Doxorubicin considered as one the most effective anticancer agents reveals its antitumor activity by induction apoptosis inhibition angiogenesis. Our study reports fo...

Successful therapeutic strategies for wound healing rely on proper vascularization while inhibiting fibrosis. However, scaffolds designed skin tissue engineering generally lack the biochemical cues that can enhance their without inducing Therefore, objective of this work is to incorporate platelet-rich plasma (PRP), a natural source angiogenic growth factors, into gelatin methacrylate (GelMA) h...

Although it is well established that tumors can induce endothelial cell mitosis and angiogenesis leading to extensive neovascularization, little is known concerning the spectrum of normal cells or tissues that may have similar inductive capabilities. A variety of developmentally active tissues were tested: mouse embryonic organ rudiments, mouse and rabbit trophoblast and placenta, and blastemal...

Synadenium umbellatum Pax, popularly known as "cola-nota", is a medicinal plant that grows in tropical regions. Latex of this plant is used to treat various diseases such as diabetes mellitus, Hansen ́s disease, tripanosomiases, leukemia and several malignant tumors. In the present study, the angiogenic activity of S. umbellatum latex was evaluated using the chick embryo chorioallantoic membrane...

1. Among eight strains or variants, included in four different immunological types of pleuropneumonia-like microorganisms, all grew on chorioallantoic membranes; those belonging to Klieneberger's Type L(5) (Sabin Type A) grew very poorly; and those included in three other types grew with varying degrees of vigor. 2. In all instances, strains of pleuropneumonia-like microorganisms tested grew be...

The synergistic effect of Hemophilus influenzae suis and swine influenza virus in the pig can be reproduced by the inoculation of these agents on the chorioallantoic membrane of 9 to 10 day old chick embryos. Two strains of human influenza virus that were studied failed to substitute for the swine virus in the synergistic reaction. No loss of synergistic effect was noted when the swine influenz...

In this work, peptides designed to selectively interact with cellular receptors involved in the regulation of angiogenesis were anchored to oligo-ethylene glycol-capped gold nanoparticles (AuNPs) and used to evaluate the modulation of vascular development using an ex ovo chick chorioallantoic membrane assay. These nanoparticles alter the balance between naturally secreted pro- and antiangiogeni...