INTRODUCTION Air leak is a well-recognized complication of advanced cystic fibrosis in older children and adults but is extremely rare in infants. To the best of our knowledge, this is the youngest reported pediatric case of an air leak from a major airway. CASE PRESENTATION A 4-month-old Yamani baby girl with a family history of cystic fibrosis initially presented with a history of a persist...

AIM To examine the gastrointestinal handling of [1-13C]palmitic acid given as the free acid by measuring the excretion of 13C label in stool in 16 healthy children and 11 patients with cystic fibrosis on their habitual enzyme replacement treatment. METHODS After an overnight fast, each child ingested 10 mg/kg body weight [1-13C]palmitic acid with a standardised test meal of low natural 13C ab...

Aim—To examine the gastrointestinal handling of [1-C]palmitic acid given as the free acid bymeasuring the excretion of C label in stool in 16 healthy children and 11 patients with cystic fibrosis on their habitual enzyme replacement treatment. Methods—After an overnight fast, each child ingested 10 mg/kg body weight [1-C]palmitic acid with a standardised test meal of low natural C abundance. A ...

OBJECTIVE To measure the effects of parents giving massage therapy to their children with cystic fibrosis to reduce anxiety in parents and their children and to improve the children's mood and peak air flow readings. METHODS Twenty children (5-12 years old) with cystic fibrosis and their parents were randomly assigned to a massage therapy or a reading control group. Parents in the treatment g...

Measurement of lung function is an important component of clinical management in cystic fibrosis (CF), but has been difficult in young children. The present study aimed to characterise the utility of the forced oscillation technique for measurement of lung function in preschool-aged children with CF in a routine clinical setting. Lung function was assessed in 56 young children (aged 2-7 yrs) wi...

background : cystic fibrosis (cf) is an autosomal recessive disorder chiefly characterized by respiratory and gastrointestinal symptoms. this study investigates whether omega-3 fatty acid affects quality of life in children with cf. materials and methods: this was a single-blind, pilot study undertaken at the cystic fibrosis center of sarvar children hospital, mashhad, iran from march 2009 unti...

Early acquisition of Pseudomonas aeruginosa is associated with a poorer prognosis in patients with cystic fibrosis. We investigated whether polymorphisms in CD14, the lipopolysaccharide receptor, increase the risk of early infection. Forty-five children with cystic fibrosis were investigated with annual bronchoalveolar lavage (BAL) and plasma sCD14 levels. Plasma sCD14 levels were significantly...