Thermosensitive chitosan (CH)-based hydrogels prepared with a mix of sodium bicarbonate and ?-glycerophosphate as gelling agents rapidly pass from liquid at room temperature to mechanically strong solid body without any crosslinker. They show excellent potential for tissue engineering applications could be interesting candidates bioprinting. Unfortunately, since gelation is not instantaneous, f...

Complex structured soft matter may have important applications in the field of tissue engineering and biomedicine. However, the discovery of facile methods to exquisitely manipulate the structure of soft matter remains a challenge. In this report, a multilayer hydrogel is fabricated from the stimuli-responsive aminopolysaccharide chitosan by using spatially localized and temporally controlled s...

Type I collagen and chitosan are two of the main biological macromolecules used to design scaffolds for tissue engineering. The former has benefits being biocompatible provides biochemical cues cell adhesion, proliferation differentiation. However, hydrogels usually exhibit poor mechanical properties difficult functionalize. Chitosan is also often biocompatible, but much more versatile in terms...

Recently, scientific and technological interest in the synthesis of novel peptide-based hydrogel materials have grown dramatically. Applications of such materials mostly concern the biomedical field with examples covering sectors such as drug delivery, tissue engineering, and production of scaffolds for cell growth, thanks to their biocompatibility and biodegradability. In this work we synthesi...

Biomedical adhesives have been found to be an attractive alternative suturing in several circumstances. However, date most of the clinically approved formulations are based on synthetic and highly reactive toxic chemicals. In this work, we aimed combine for first time bioactive properties cationic polysaccharide chitosan its intrinsic electrostatic binding negatively charged tissues with biocom...

Chitosan (CS) has generated considerable interest for its desirable properties and wide applications. Hydrogel has been proven to be a major and vital form in the applications of CS materials. Among various types of CS hydrogels, physical cross-linked CS hydrogels are popular, because they avoided the potential toxicity and sacrifice of intrinsic properties caused by cross-linking or reinforcem...