نتایج جستجو برای: chitosan nanoparticles
تعداد نتایج: 121183 فیلتر نتایج به سال:
In Vivo Assessment of Clobetasol Propionate-Loaded Lecithin-Chitosan Nanoparticles for Skin Delivery
The aim of this work was to assess in vivo the anti-inflammatory efficacy and tolerability of clobetasol propionate (CP) loaded lecithin/chitosan nanoparticles incorporated into chitosan gel for topical application (CP 0.005%). As a comparison, a commercial cream (CP 0.05% w/w), and a sodium deoxycholate gel (CP 0.05% w/w) were also evaluated. Lecithin/chitosan nanoparticles were prepared by se...
The study reported here aimed to develop an optimized nanoparticle delivery system for amphotericin B (AmpB) using a polyelectrolyte complexation technique. For this, two oppositely charged polymers presenting anti-leishmanial activity - chitosan (Cs) and chondroitin sulfate (ChS) - were used: Cs as a positively charged polymer and ChS as a negatively charged polymer. The chitosan (NQ) nanopart...
In this paper, Fe3O4-chitosan nanoparticles were prepared by the immobilization of chitosan on the surface of Fe3O4 nanoparticles. Then, the 5-substituted hydantoins were synthesized from the condensation of aldehyde derivatives, ammonium carbonate and zinc cyanide as a well-known cyanating agent by the magnetic Fe3O4-chitosan nanoparticles under neat conditions. Fe3O4-Chitosan nanocatalyst as ...
A new approach to the synthesis of highly stable aqueous colloids of coordination polymer nanoparticles was developed by using water-soluble chitosan beads as template and as stabilizing agent. The method consists in the synthesis of nanocomposite beads containing cyano-bridged coordination polymer nanoparticles via step-by-step coordination of the metal ions and the hexacyanometallate precurso...
Ferrite nanoparticles were synthesized at around 4°C~25°C and coated during the synthesis process with biocompatible and biodegradable polymers, dextran or chitosan. The size of ferrite nanoparticles was determined to be 7.51nm by DLS (Dynamic Light Scattering) and TEM (Transmission Electron Microscope). The size of coated nanoparticles was increased up to 128.6nm and 67nm for dextran and chito...
Hybrid hollow nanospheres of chitosan-silica templated by chitosan-poly(acrylic acid) nanoparticles are fabricated in a complete aqueous system, which provide a pH-sensitive switch in physiological and sub-cell environments for the release of loaded drug.
Curcumin (CU) loaded solid lipid nanoparticles (SLNs) of fatty acids (FA) were prepared with a coacervation technique based on FA precipitation from their sodium salt micelles in the presence of polymeric non-ionic surfactants. Myristic, palmitic, stearic, and behenic acids, and different polymers with various molecular weights and hydrolysis grades were employed as lipid matrixes and stabilise...
Objective(s): This study considered the combination of chitosan nanoparticles with antioxidant-antibacterial fraction extracted from Lactobacillus casei and investigation of possible increasing of antibacterial activity of the fraction in hybrid nanoparticle and the effect of the fraction on the stability of chitosan nanoparticles. Methods: Extra...
Introduction: Antibiotic-carrying nanoparticles have cytotoxic effects on drug-resistant bacteria. The aim of the present study was to evaluate the effect of chitosan nanoparticles carrying amoxicillin and clavulanic acid on the viability of staphylococcus aureus strains. Materials & Methods: In this study, chitosan nanoparticles were prepared by ionic gelation method and were loaded by amo...
Introduction: Among several tuberculosis vaccine candidates for replacement of BCG, ESAT-6 protein has a special role. Since mycobacterium tuberculosis infection most often attacks the lungs, intranasal rout can be regarded as appropriate methods for tuberculosis vaccines and drug delivery. One of the appropriate systems for intranasal vaccine delivery is using biodegradable nanoparticles. Amon...
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