In the present study, we determined levels of chlorinated pesticide residues in surface water samples collected from Charsadda district (KPK, Pakistan). SPME-GC-ECD with COMBI PAL CTC autosampler was used for extraction and analysis 20 organochlorine pesticides samples. For maximum efficiency SPME procedure, several parameters were studied, including desorption time fiber, solution pH, agitatio...

The occurrence and persistence of OC residues in both animal fat and in soil is reviewed. These chemicals have caused problems in production of pasture and grain for livestock. Management strategies to give short term guidelines to graziers are described. Attempts to increase the rate of breakdown in the soil under Australian conditions by varying frequency of cultivation, by addition of lime o...

Seven selected insecticides were applied to three substrates and bioassayed for barrier efficacy and toxicity against the Formosan subterranean termite, Coptotermes formosanus Shiraki, originating from colonies that differed in their tolerance to the insecticides. A profound substrate effect was seen with all insecticides tested. Sand was the most difficult substrate to penetrate and caused fas...

For 26 months, we fed baboons a high saturated fat, high cholesterol diet that contained very low concentrations of four common pesticides (chlordane, parathion, diazinon, and carbofuran). We detected no effect of pesticides on body weight, serum lipid, or lipoprotein cholesterol concentrations, or experimental atherosclerosis. We then examined the associations of serum lipid and lipoprotein ch...

Seasonal and geographic studies of transmissible sarcoma in Maryland softshell clams, Mya arenaria, were carried out from 1984 to 1988. Three major epizootics occurred in our sampling location during this time, resulting in prevalences as high as 90%, with comparable mortalities in other high prevalence areas. The disease invaded populations of large adult clams first, later spreading to the sm...

Estrogen-related receptor (ERR) a-1 shares a high amino acid sequence homology with estrogen receptor a. Although estrogens are not ligands of ERRa-1, our recent results suggest that toxaphene and chlordane, two organochlorine pesticides with estrogen-like activity, behave as antagonists for this orphan nuclear receptor. The two compounds increased ERRa-1-mediated expression of the reporter enz...