This paper describes the effect of dipyridamole (DIP) on the cytotoxicity of cisplatin in HEp-2 human larynx cancer cells in vitro and the nature of the interaction between cisplatin and dipyridamole. Cytotoxic assays were performed to obtain the IC50 for cisplatin. The cells were treated with 0, 20, 40, 80, 120 or 200 microM cisplatin, with or without a single concentration of DIP and incubate...

BACKGROUND AND PURPOSE Recent studies have shown that several nonmotor symptoms differ between Parkinson's disease (PD) and drug-induced parkinsonism (DIP). However, there have been no reports on cardiovascular autonomic function in DIP, and so this study investigated whether cardiovascular autonomic function differs between PD and DIP patients. METHODS This study consecutively enrolled 20 DI...

In order to determine the extent of acaricide resistance in the eastern region of the Eastern Cape Province 1-, 2- and 3-host ticks were collected from cattle at 59 dip-tanks over a period of 2 years. These ticks were tested for resistance against 3 compounds, namely amitraz, cypermethrin and chlorfenvinphos. The Shaw Larval Immersion Test detected emerging resistance to amitraz in Rhipicephalu...

Schistosomiasis is one of the most prevalent parasitic infections worldwide. Establishment of sensitive assays to detect schistosomiasis in situations with low transmission is crucial. The present study aimed to estimate the current status of S. haematobium infection in different Egyptian localities. Urine samples were collected from 960 asymptomatic men from Great Cairo (low-endemic) and Fayou...

We demonstrate a method for determining the spectral purity of single photons. The technique is based on the Hong–Ou–Mandel (HOM) interference between a single-photon state and a suitably prepared coherent field. We show that the temporal width of the HOM dip is related not only to the reciprocal of the spectral width but also to the underlying quantum coherence. Therefore, by measuring the wid...

Chloroform is a drinking water contaminant that has been demonstrated to be carcinogenic to mice and rats resulting in an increased incidence of liver and kidney tumors, respectively. The mechanism of chloroform carcinogenicity might be by tumor initiation and/or promotion. Since induction of ornithine decarboxylase (ODC) activity has been proposed as a molecular marker for tumor promoters, we ...

The environmental irritant chloroform, a naturally occurring small volatile organohalogen, briefly became the world’s most popular volatile general anesthetic (VGA) before being abandoned because of its low therapeutic index. When chloroform comes in contact with skin or is ingested, it causes a painful burning sensation. The molecular basis for the pain associated with chloroform remains unkno...

Two urine dip-stick assays for glucose were studied and compared to a quantitative hexokinase procedure. We determined sensitivity, specificity, predictive value of "normal" and "abnormal" dip stick results, assay efficiency, technologist precision, and method association. Precision was poor. Attempts to estimate urine glucose concentration with the dip sticks frequently produced gross inaccura...

We propose an ultra-short-term dynamic interval predictor (DIP) of solar irradiance. Our DIP relies on experimentally observed correlations between the derivative of the solar irradiance and the forecast error in the next time-step. The main originalities of this DIP are (i) its independence from the method used for the point forecast of solar irradiance, (ii) its independence from the error di...