This work presents the results of applying genetic algorithms, in selecting the more relevant features present in chromatograms of polyphenolic compounds, obtained from a high performance liquid chromatograph with aligned photodiodes detector (HPLCDAD), of samples of Chilean red wines Cabernet Sauvignon, Carmenere and Merlot. From the 6376 points of the original chromatogram, the genetic algori...

BACKGROUND A major challenge in high-throughput clinical and toxicology laboratories is the reliable processing of chromatographic data. In particular, the identification, location, and quantification of analyte peaks needs to be accomplished with minimal human supervision. Data processing should have a large degree of self-optimization to reduce or eliminate the need for manual adjustment of p...

Ultrathin-layer chromatography (UTLC) is a recently developed analytical method intended for compact, rapid separations of nanolitre analyte volumes. Optimizing this method's performance requires new measurement techniques compatible with the millimetre length scales and rapid separation dynamics observed in UTLC. We have designed, implemented and characterized a measurement system which record...

The concentration of alamethicin in aqueous solutions was quantitated using measurements of the spot area on thin-layer chromatograms. These data were utilized to measure a partition coefficient of 17 for alamethicin in a phospholipid membrane-water system under equilibrium dialysis conditions.

Phosphoglyceride phosphorus is readily determined directly on silica gel removed from thin-layer chromatograms, without elution, by a nondigestive procedure with a sulfuric-periodic acid reagent. The method is specific for hydrolyzable phosphoglyceride containing two acid-hydrolyzable groups. Cariolipin reacts only partially, while sphingomyelin, diether lecithin, and phosphonate cephalin fail ...

A new antibiotic, victomycin, is active against a variety of Gram-positive and Gram-negative bacteria, and also has in vivo activity against solid Sarcoma 180 and Ehrlich ascites carcinoma. It belongs to the phleomycin-bleomycin group of antibiotics and has been differentiated from all known phleomycins and bleomycins by its physicochemical properties and thin-layer chromatograms.

Diuretic abuse has been invoked as the cause of idiopathic oedema. In this study, eight patients with idiopathic oedema were studied. Symptoms and weight variation continued despite the proven absence of diuretics in seven of them as determined by urinary chromatograms. Idiopathic oedema cannot therefore be attributed to diuretic use alone.

2 LCMS feature detection step by step using cosmiq 2 2.1 The Input . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 Combination of mass spectra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.3 Detection of relevant masses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2.4 Generation and combination of extracted ion chrom...

Urinary amino-acid chromatograms from 23 patients with megaloblastic anaemia have been studied before and after therapy. The most consistent abnormality was an increased taurine or increased taurine/glycine ratio. This was not related directly to deficiency of vitamin B(12) or folic acid or to the degree of anaemia.