نتایج جستجو برای: chromosome duplication

تعداد نتایج: 136802  

Journal: :Genetics 2000
J D Lieb C O de Solorzano E G Rodriguez A Jones M Angelo S Lockett B J Meyer

The dosage compensation machinery of Caenorhabditis elegans is targeted specifically to the X chromosomes of hermaphrodites (XX) to reduce gene expression by half. Many of the trans-acting factors that direct the dosage compensation machinery to X have been identified, but none of the proposed cis-acting X chromosome-recognition elements needed to recruit dosage compensation components have bee...

Journal: :Molecular and cellular biology 2006
Futoshi Suizu Akihide Ryo Gerburg Wulf Jormay Lim Kun Ping Lu

Phosphorylation on Ser/Thr-Pro motifs is a major mechanism regulating many events involved in cell proliferation and transformation, including centrosome duplication, whose defects have been implicated in oncogenesis. Certain phosphorylated Ser/Thr-Pro motifs can exist in two distinct conformations whose conversion in certain proteins is catalyzed specifically by the prolyl isomerase Pin1. Pin1...

Journal: :Molecular biology and evolution 2011
Kelly A Dyer Brooke E White Michael J Bray Daniel G Piqué Andrea J Betancourt

In contrast to the rest of the genome, the Y chromosome is restricted to males and lacks recombination. As a result, Y chromosomes are unable to respond efficiently to selection, and newly formed Y chromosomes degenerate until few genes remain. The rapid loss of genes from newly formed Y chromosomes has been well studied, but gene loss from highly degenerate Y chromosomes has only recently rece...

2011
Lucie Fouvry David Ogereau Anne Berger Frederick Gavory Catherine Montchamp-Moreau

Sex-ratio distorters are X-linked selfish genetic elements that facilitate their own transmission by subverting Mendelian segregation at the expense of the Y chromosome. Naturally occurring cases of sex-linked distorters have been reported in a variety of organisms, including several species of Drosophila; they trigger genetic conflict over the sex ratio, which is an important evolutionary forc...

Journal: :Proceedings of the National Academy of Sciences 1977

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