Nasal cytology is a very useful diagnostic tool in nasal disorders, being able to detect both the cellular modifications of the nasal epithelium caused by either allergen exposure or irritative stimuli (that may be physical or chemical, acute or chronic), or inflammation. Over these past few years, nasal cytology has allowed to identify new disorders, such as the non-allergic rhinitis with eosi...

Recent studies have reported an association between systolic blood pressure (BP) and rhinitis. The prevalence of allergic rhinitis is 20% to 30% in Japan. The present cross-sectional study was performed to assess the relation between BP and allergic rhinitis in a sample of 2,292 male adolescent high school students who attended the annual school health examination. Of the 2,292 students (mean a...

Allergic rhinitis affects more than 20% and is responsible for very high direct and indirect costs. Nasal corticosteroids are the principle pharmaceutical option for the treatment of allergic rhinitis. They are more effective than all other therapeutic options and in addition to improving symptoms of allergic rhinitis they also improve quality of life in patients suffering from allergic rhiniti...

Allergic rhinitis is one of the most common chronic disorders in the United States, causing patients significant discomfort and interfering with quality of life and functioning. Histamine is the primary mediator in the development of allergic rhinitis symptoms and is a primary therapeutic target. Guidelines, both in the United States and globally, recommend antihistamines as first-line therapy ...

Background. Toll-like receptors (TLRs) represent a family of evolutionarily conserved proteins, that represent a fundamental link between innate and adaptive immune responses. Aim. The purpose of this study was to investigate the expression of TLR4 and TLR9 in the normal nasal mucosa and in the mucosa of subjects with different phenotypes of rhinitis. Methodology. A confocal analysis of TLR4 an...

BACKGROUND Anticholinergic agents, specifically the quaternary salt of atropine, are currently being recommended for chronic rhinitis and the common cold. OBJECTIVE To evaluate the efficacy and safety of 50- and 75-microg doses of atropine sulfate as a nasal spray in perennial allergic rhinitis. METHODS A placebo-controlled, double-blind study compared 2 doses of atropine nasal spray given ...

BACKGROUND It has been well known that pediatric allergic rhinitis was associated with poor performance at school due to attention deficit. However, there were no cohort studies for the effect of treatment of allergic rhinitis on attention performance in pediatric population. Thus, the aim of this study was to investigate whether attention performance was improved after treatment in children wi...

inhalation of fungal spores is shown to participate in the development of allergic rhinitis symptoms. in this study, relation between presence of alternaria in the human nasal cavity and allergic rhinitis is assessed. in a case-control study, 58 allergic rhinitis patients were compared with a well-matched control group of fifty healthy volunteers for sensitization to alternaria (by skin prick t...

The concept of the burden of a disease is an interesting one because it encompasses concepts beyond our traditional view of illness, i.e. pain and suffering. A disease, especially a chronic one like allergic rhinitis, has an impact on a sufferer through both the direct and indirect symptoms, complications (including health-related quality of life) and cost (direct, indirect and intangible costs...