GABAergic neurotransmission is highly plastic, undergoing dynamic alterations in response to changes in the environment, such as following both acute and chronic stress. Stress-induced plasticity of GABAergic inhibition is thought to contribute to changes in neuronal excitability associated with stress, which is particularly relevant for stress-related disorders and seizure susceptibility. Here...

Stress fractures of the third metacarpal bone (McIII) are a common cause of lameness in Thoroughbred racehorses. The most commonly described location is the mid-dorsolateral cortex (Copelan 1979; Richardson 1984, 1999; Stashak 1987; Stover et al. 1988; Cervantes et al. 1992; Pilsworth and Shepherd 1997; Stover 1998; Sullins 1998), but they also occur distally and proximally in the dorsal cortex...

objective(s): stress induces many homeostatic aberrations which are followed by lifelong allostatic responses. epilepsy is developed or influenced by different environmental factors, i.e. prenatal stress which makes many contradictory developmental changes in seizure threshold and intensity. we investigated the potential seizure response of the rat offspring to prenatal stress; the stress which...

this paper presents the effect of high environmental heat on behavior of the male charles foster rats. eighty rats were divided into three groups, subjected to (i) acute heat stress (ii) chronic heat stress and (iii) handling control group. animals were exposed to the hot environment in a biological oxygen demand incubator at 38 ± 1ºc (relative humidity 45-50%) for four hours of continuous sing...

chronic lymphocytic leukemia (cll) and chronic myeloid leukemia (cml) are the most common leukemias of the elderly (>43 year). however, the sequential occurrence of cml followed by cll in the same patient is extremely rare. in our report, a 52-year-old female was diagnosed with cll (type of bone marrow (bm) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months ...