Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting: St. Luke’s Hospital, Malta; January May 2001. Subjects: 226 patients, aged 60 years or over, with a history of chronic stable angina and a dis...

OBJECTIVES To assess the effect of clinical presentation on functional prognosis in patients with syndrome X. DESIGN A prospective study. Patients with syndrome X presenting with unstable angina and stable angina were followed up with a questionnaire to examine their functional state. PATIENTS 41 patients with syndrome X and unstable angina and 41 patients with syndrome X and stable angina....

Percutaneous coronary intervention (PCI) has played an integral role in the therapeutic management strategies for patients who present with either acute coronary syndromes or stable angina pectoris. The COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial enrolled patients with chronic stable angina and at least 1 significant (> or =70%) angiographic coro...

AIM This paper is a report of a qualitative study conducted as part of a randomized controlled trial comparing a lay-facilitated angina management programme with usual care. Its aim was to explore participants' beliefs, experiences, and attitudes to the care they had received during the trial, particularly those who had received the angina management intervention. BACKGROUND Angina affects ov...

BACKGROUND Heart rate reduction should benefit patients with chronic stable angina by improving myocardial perfusion and reducing myocardial oxygen demand. This study evaluated the antianginal and antiischemic effects of ivabradine, a new heart rate-lowering agent that acts specifically on the sinoatrial node. METHODS AND RESULTS In a double-blind, placebo-controlled trial, 360 patients with ...

The recently published American College of Cardiology/ American Heart Association 2002 Guideline Update for Management of Patients with Chronic Stable Angina contains a comprehensive review of medications used for this purpose (2). Three classes of agents reviewed (beta-blockers, calcium antagonists, and nitrates) are effective for angina on the basis of altering the supply-demand imbalance cre...

CONTEXT Many patients with chronic angina experience anginal episodes despite revascularization and antianginal medications. In a previous trial, antianginal monotherapy with ranolazine, a drug believed to partially inhibit fatty acid oxidation, increased treadmill exercise performance; however, its long-term efficacy and safety have not been studied in combination with beta-blockers or calcium...

Disorders of the Pericardium Pericardial Effusion Pericarditis Acute Pericarditis Chronic Pericarditis With Effusion Constrictive Pericarditis Coronary Heart Disease Coronary Circulation Pathogenesis of Coronary Heart Disease Chronic Ischemic Heart Disease Stable Angina Variant Angina Silent Myocardial Ischemia Acute Coronary Syndromes Unstable Angina/Non–ST-Segment Elevation Myocardial Infarct...