A large fraction of hereditary demyelinating neuropathies, classified as Charcot-Marie-Tooth disease type 1A, is associated with misexpression of peripheral myelin protein 22. In this study, we characterized morphologic and biochemical changes that occur with diseaseprogression in neuromuscular tissue of Trembler-J mice, a spontaneous rodent model of Charcot-Marie-Tooth disease type 1A. Using a...

Two methods for genotyping hepatitis C virus (DNA enzyme immunoassay [DEIA] and line probe assay [Inno-LiPA HCV I and II]) were compared on 120 samples and of these 87% were assigned to the same subtype by both assays. There were 15 subtyping discrepancies which involved 5% of type 1 isolates and 90% of type 2 isolates. Amplified products from the core and 5' untranslated regions (UTR) were seq...

BACKGROUND Recent reports in the scientific and lay press have suggested that bile duct injuries during laparoscopic cholecystectomy are common in Ontario. The reports were based on administrative data collected by hospital medical records departments and the Canadian Institute for Health Information (CIHI). The current study involved a direct inspection of hospital records to determine if the ...

OBJECTIVE To see if a public awareness campaign might be justified around Halloween with regard to the dangers of egg throwing. METHOD A prospective study was carried out of all patients who attended the St Paul's Eye Unit's Primary Care Department with ocular injuries resulting from a thrown egg over a 14-month period from November 2004. All injuries were classified as minor, intermediate or...

Background: Accidents are a major cause of death, injury and disability. This study was conducted to examine the epidemiology of injuries due to accidents in units affiliated with Torbat Heydariyeh University of Medical Sciences, Iran. Materials and Methods: In this cross-sectional study, all patients in units affiliated with Torbat Heydariyeh University of Medical Sciences were studied from M...

The wild-relative gene pools of wheat are a rich source of genetic variation for wheat improvement.Karyotypes of eight genotypes of Triticum monococcum subsp. aegilopoides and eight genotypes of Aegilops cylindrica,which grown wild next to each other in different regions in the west of Iran were studied. Root tips were treated in α-bromonaphthalene solution, fixed in chromic acid-formaldehyde f...

INTRODUCTION Recently, researchers have been considering as adverse prognostic factors in primary glioblastomas not only clinical indicators but also various cellular, genetic and immunological markers. The aim of the present article was to report a case of primary glioblastoma multiforme with poor survival in a patient after surgical intervention, and to determine the unfavorable prognostic ma...

abstract: genotyping of the hepatitis c virus (hcv) is important for designing therapeutic strategies and regional specific diagnostic assays. the aim of this study was to identify the hcv genotypes in hcv infected blood donors. this is the first report on hcv genotypes in blood donors in iran. in this cross-sectional study, 103 blood donors with hepatitis c were investigated for hcv genotypes....

Modifications of a Type 1a external skeletal fixator (ESF) frame were evaluated by alternately placing transfixation pins on opposite sides of the connecting rod (Type 1a-MOD) or by placing additional connecting rods on either of the two inside (Type 1a-INSIDE) or two outside (Type 1a-OUTSIDE) transfixation pins. The objective of this study was to evaluate the stiffness of these modifications i...

BACKGROUND The purpose of this study was to identify the relationship between the deeper and faster chest compressions suggested by the 2010 cardiopulmonary resuscitation guidelines and complications arising from chest compressions, using multi-detector computed tomography. METHODS We performed a retrospective analysis of prospective registry data. This study was conducted with in- and out-of...