OBJECTIVES The objective was to evaluate inflammation in echolucent carotid artery plaques. BACKGROUND Ultrasound echolucency of carotid artery plaques has been proven to differentiate patients at high risk of stroke. On the other hand, positron emission tomography (PET) of plaques with the use of [(18)F]-fluorodeoxyglucose (FDG) identifies highly inflamed plaques, and the combination of mole...

BACKGROUND Identification and differentiation of coronary atherosclerotic plaques may improve risk stratification for incident coronary events. OBJECTIVE We investigated the ability of dual-source computed tomography (CT) to depict and characterize atherosclerotic coronary plaques. METHODS Contrast-enhanced CT was performed in 25 human heart specimens with a total of 322 histologically dete...

conclusion safire reconstruction provided better coronary image quality and displayed the number, morphology, and surrounding lumen of calcium plaques more accurately than traditional fbp reconstruction, with safire3 achieving the best results. results the subjective ratings of image quality using safire1–safire5 reconstructions were significantly higher than those using fbp, with safire3 achie...

Background: Despite the existence of various imaging methods, the accurate diagnosis of many neurodegenerative diseases is still controversial. The use of advanced imaging techniques, such as the diffusion weighted imaging can be help the early detection of MS and evaluation of the treatment efficacy in these patients. Materials and method: 24 MS patients with acute attack and thirty healthy s...

background and objective: ischemic heart disease (ihd) following atherosclerosis is the most common cause of cardiac deaths world wide. we aimed to investigate the pathologic features of atherosclerosis in non cardiac death cases to have an estimate of atherosclerosis prevalence in mashad (north east of iran). patients and methods : this descriptive (cross sectional) study was done, during octo...

the aim of this study was to investigate the iron concentrations in serum and carotid plaque in patients with different morphology of carotid atherosclerotic plaque and compared with other metal ions. carotid endarterectomy due to the significant atherosclerotic stenosis was performed in 91 patients. control group consisted of 27 patients, without carotid atherosclerosis. atherosclerotic pla...

A series of clear mutants of the temperate phage 16-3 of Rhizobium meliloti were isolated that included various point and deletion mutants of the C cistron, coding for the phage repressor. It was observed that recombinant genotypes, such as c(+) and ti (temperature-sensitive allele), which form turbid plaques, can be detected quantitatively as lysogenic colonies and scored even at frequencies a...

We report a method for obtaining turbid plaques of the lactococcal bacteriophage TP901-1 and its derivative TP901-BC1034. We have further used the method to isolate clear plaque mutants of this phage. Analysis of 8 such mutants that were unable to lysogenize the host included whole genome resequencing. Four of the mutants had different mutations in structural genes with no relation to the genet...