Abstract In the present study, antibiotic resistance profiles and biofilm forming abilities of 9 Listeria monocytogenes isolates obtained from out 30 retail meat samples were determined, effect commercial white vinegar on these virulence factors in exposed to subMIC concentrations investigated. All found be resistant cefotixin oxacillin, 8 (26.6%) clindamycin, 1 isolate (3.3%) rifampicin, was s...

Clindamycin, a semi-synthetic antibiotic of the lincomycin family, at a dose of 450 mg eight-hourly for three days in adults cured five out of 10 patients moderately ill with chloroquine-resistant falciparum malaria. Combination therapy with full-dose quinine and clindamycin for three days cured all four patients so treated who were followed up, and with half dosage three out of five patients w...

Bacterial counts were carried out on the faeces of 160 patients receiving clindamycin or lincomycin treatment for bacterial infections. In all the patients the total bacteroides count was significantly reduced while strains of Enterobacteriaciae, yeasts, and streptococci were correspondingly increased. Severe diarrhoea developed in 25 (16%) patients, but this could not be related to a change in...

The comparative in vitro activity of RU 64004 (also known as HMR 3004), a new ketolide antibiotic, was tested by agar dilution against approximately 500 gram-positive organisms, including multiply resistant enterococci, streptococci, and staphylococci. All streptococci were inhibited by < or = 1 microg of RU 64004 per ml. The ketolide was more potent than other macrolides against erythromycin A...

We examined the resistance phenotype and the genetic basis of lincosamide modification in 25 clinical isolates of Staphylococcus spp. inactivating lincomycin and clindamycin. The strains were resistant to high levels of lincomycin but remained susceptible to clindamycin. However, MBCs and inoculum effects showed that the activity of clindamycin was impaired. The distribution in these strains of...

Staphylococcus haemolyticus BM4610 was resistant to high levels of lincomycin and susceptible to macrolides, clindamycin, and streptogramins. This resistance phenotype, not previously reported for a human clinical isolate, was due to inactivation of the antibiotic. The gene conferring resistance to lincomycin in strain BM4610 was carried by a 2.5-kilobase plasmid, pIP855, which was cloned in Es...

Objective-To evaluate the efficacy and safety of a 3 day course of intravaginal clindamycin 2% cream for the treatment ofbacterial vaginosis. Design-A prospective, randomised, double-blind placebo controlled study. Setting-Departments of genitourinary medicine at Birmingham, Nottingham, Liverpool, Swansea, Leeds, Walsall, Stoke Mandeville, Southampton, Plymouth, Bishop's Stortford and Glasgow. ...

history, presented with acute-onset midchest pain, aggravated by swallowing. The pain had begun 6 days previously when the man was lying down. The patient had taken the last dose of three 300-mg clindamycin tablets for mild folliculitis, 1 hour before onset of the symptoms. Self-prescribed pantoprazole – 20mg for 3 days – had provided no relief. Physical examination revealed no abnormalities. U...

For quite a long time, mainly due to fewer treatment options, Clindamycin have been regarded as an alternative drug effectively manage all Staphylococcus aureus infections. Strains with inducible clindamycin resistance (iMLSB phenotype) raise concerns because therapeutic failure may occur during treatment. is mostly in treating serious infections that cannot be treated by other antibiotics, it ...