Proper and timely segregation of the cellular genome is a prime requirement all cell division programs. Mis-segregation chromosomes resulting aneuploidy lead to several clinical consequences. Over years, shugoshin has emerged as key protein factor involved in genetic material dividing cells. Deletion or an altered level reported human malignancies; result, now emerging important tumor-associate...

objective: patients with bipolar mood disorder constitute a relatively large number of individuals hospitalized in psychiatric hospitals. this disorder is highly co-morbid with other psychiatric disorders and may effect their clinical course. the goal of this study was to determine the co-occurrence rate of anxiety disorders and substance abuse with bipolar mood disorders and their impact on cl...