Sir, We read with great interest the recent article published in Brain by Pittock et al. (2010), who reported eight patients with clinical, radiological and pathological features of brainstem involvement responsive (but dependent) to steroid treatment. All the reported patients shared common clinical and MRI findings: gait ataxia, diplopia, patchy increased T2 signal and gadolinium enhancement ...

The shape of the protein surface dictates what interactions are possible with other macromolecules, but defining discrete pockets or possible interaction sites remains difficult. First, there is the problem of defining the extent of the pocket. Second, one has to characterize the shape of each pocket. Third, one needs to make quantitative comparisons between pockets on different proteins. An el...

DURING the last two centuries the treatment of amblyopia ex anopsia in cases of strabismus has made considerable progress. One of the earliest forms of treatment was occlusion of the fixing eye. This was first carried out by Buffon (1743), who also showed the need for correction of the refractive error by means of spectacles. More than a century later, Javal (1896) thought that squint was prima...

Over the past three and half decades, tremendous gains have been achieved in the speech and hearing sciences. These conceptual and technological advances have improved the lives of children with hearing loss in ways that would have seemed inconceivable three or four decades ago. The goal of this paper is to provide an overview of the field of pediatric amplification in the 1970s, a review of pr...

Cesarean delivery (CD) is one of the most common procedures performed in the United States, accounting for 32% of all deliveries. Postpartum surgical site infection (SSI), wound infection and endometritis is a major cause of prolonged hospital stay and poses a burden to the health care system. SSIs complicate a significant number of patients who undergo CD - 2-7% will experience sound infection...

BACKGROUND Infection control is a key issue in podiatry as it is in all forms of clinical practice. Airborne contamination may be particularly important in podiatry due to the generation of particulates during treatment. Consequently, technologies that prevent contamination in podiatry settings may have a useful role. The aims of this investigation were twofold, firstly to determine the ability...

OBJECTIVE To screen out adult patients for HBV and HCV infections visiting Khyber College of Dentistry Peshawar (KCD) for different dental treatments and to identify the associated risk factors. METHOD This cross-sectional study was conducted at Khyber College of Dentistry, Peshawar in the year 2013. A total of 1540 patients >15 years, visiting KCD for seeking different dental treatments were...