espanolEl liquen escleroso es una enfermedad inflamatoria cronica, de etiologia desconocida, que afecta la piel y las mucosas. Presentamos un caso paciente con genital extragenital concomitante, presento buena respuesta al tratamiento clobetasol tracrolimus topico en region genital, fototerapia ultravioleta B banda angosta (UVB-BA) lesiones extragenitales. EnglishLichen sclerosus is a chronic i...

Our main objective is to study the efficacy, safety and influence on inflammatory factors of secukinumab in treatment plaque psoriasis. A total 120 patients admitted Tonglu People’s Hospital from December 2021 November 2022 were selected as objects this drug comparison divided into observation group control group. The drugs used compound clobetasol propionate ointment. lasted for 4 w. effects t...

This work aimed to investigate the feasibility to design: (a) a mucoadhesive interpolyelectrolyte complex (IPEC) loaded with clobetasol propionate (CP) intended to treat oral lichen planus and (b) individuate an orodispersible dosage form suitable for its administration. IPECs were synthesized by mixing Eudragit® E PO (EPO) and different grades of cross-linked polyacrylate derivatives, in diffe...

An 86-year-old man developed a suspected severe erythroderma during treatment with silodosin (dosage unknown) for benign prostatic enlargement. Two weeks after starting silodosin, he developed a total-body scaling dermatitis. A biopsy was planned but the patient improved at his subsequent visit and it was not taken. Silodosin was discontinued and the patient received UVB phototherapy, clobetaso...