نتایج جستجو برای: coa reductase inhibitors
تعداد نتایج: 246262 فیلتر نتایج به سال:
Hyperhomocysteinemia is an independent risk factor for cardiovascular disorders. Elevated plasma homocysteine (Hcy) concentration is associated with other cardiovascular risk factors. We previously reported that Hcy stimulated cholesterol biosynthesis in HepG2 cells. In the present study, we investigated the underlying mechanisms of Hcy-induced hepatic cholesterol biosynthesis in an animal mode...
An improved method for the chemical synthesis of HMG-CoA is described. The procedure is designed to prevent the formation of 3-acetoxy-HMG-CoA.
Malaria caused by Plasmodium falciparum , remains one of the most fatal parasitic diseases that has affected nearly a third world’s population. The major impediment to treatment malaria is emergence resistance P. parasite current anti-malaria therapeutics such as Artemisinin (ART)-based combination therapy (ACT). This resulted in countless efforts develop novel will counter this with aim contro...
A simple and rapid mixed-phase method for the quantitative assay of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase and a procedure for the efficient reactivation of Mg-ATP-inactivated microsomal HMG-CoA reductase by potato acid phosphatase are described. The mixed-phase assay entails the direct addition of the acidified, deproteinized incubation mixture to a toluene-based scintillation fluor. T...
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