Acoustic trauma not only produces temporary and permanent hearing loss but is a common cause of chronic tinnitus. Recent work indicated a possible role for the transient receptor potential channel vanilloid subfamily type 1 (TRPV1) in modulating the effects of cochlear injury. In our research, we investigated the effects of acoustic damage on TRPV1 expression in spiral ganglion neurons of adult...

OBJECTIVE To describe intracochlear insertion trauma caused by three perimodiolar cochlear implant electrodes. STUDY DESIGN Descriptive histological study of 15 human cadaver temporal bones. METHODS Fifteen cadaver temporal bones underwent surface preparation and were implanted with one of the following perimodiolar electrode arrays: Combi 40+PM (MedEl Corporation), HiFocus II (Advanced Bio...

Introduction Sudden sensorineural hearing loss (SSNHL) involves an acute unexplained hearing loss, nearly always unilateral, that occurs over less than a 72-hour period. SSNHL pathogenesis is not yet fully understood. Cochlear vascular occlusion has been proposed as a potential mechanism of hearing damage and cochlear ischaemia has been related to alterations of cochlear microvessels. In additi...

UNLABELLED Sensorineural hearing loss, which is limited to the cochlear basal turn, due to acute or chronic otitis media has been reported in clinical and experimental studies. In the present study, the effect of intratympanic dexamethasone on endotoxin-induced cochlear damage was investigated by measuring the cochlear blood flow and hearing. MATERIALS AND METHODS Ten male Sprague-Dawley rats...

CONCLUSION Unilateral congenital deafness with a volume reduction in cochlear nucleus (CN) induced changes in the calcium-binding proteins (CaBPs) in the contralateral superior olivary complex (SOC) in the rat. With the loss of neurons and a volume reduction in the CN, a decrease in the input to the contralateral SOC may occur, which results in the down-regulation of CaBPs in these nuclei. This...

Objectives: This study examined the relationship between working and short-term memory performance, and their effects on cochlear implant outcomes (speech perception and speech production) in cochlear implanted children aged 7-13 years. The study also compared the memory performance of cochlear implanted children with their normal hearing peers. Methods: Thirty-one cochlear impl...

Aim: The most effective method of treatment for patients with severe hearing loss is cochlear implantation (CI), in which various non-standard surgical situations can occur, as well early or late complications. Purpose: to conduct an analysis complications and during CI develop recommendations their avoidance. Materials methods: A retrospective 138 disease histories adults (7) children (131) bi...

introduction: cochlear implantation can facilitate the development of communication skills in children with profound hearing loss. the objectives of our study were to determine the average ages at suspicion and diagnosis of hearing loss, amplification, intervention, and performing the cochlear implantation and to investigate the effects of the parents’ level of education and economic circumstan...