This study focused on the assessment of a program recently developed for helping patients with moderate Alzheimer's disease engage in computer-mediated verbal reminiscence (Lancioni et al., 2014a). Sixteen participants were involved in the study. Six of them used the original program version with the computer showing a virtual partner posing questions and providing attention and guidance. The o...

The Alzheimer’s disease (AD) is a progressive and degenerative disease of the brain which causes a serious impairment over its two main activities: thinking and memory. According to Celsis (Celsis, 2000), AD is the most common form of dementia among the elderly population, comprising up to 75% of all dementia cases. AD causes a gradual loss of intellectual abilities with deterioration in cognit...

Alzheimer’s disease (AD) is neurodegenerative disorder common among elderly involving deficits in memory and cognition. There has been a long history of research and medical practice in AD worldwide, during which different facts came into light. During recent decades with new technologies being integrated, progress has been made in finding new genes responsible for AD, but diagnosis and treatme...

BACKGROUND AND PURPOSE The apolipoprotein E4 allele (APOE4) associates with increased dementia risk, and hypertension may associate with mild cognitive deficits. We examined whether nondemented stroke patients with (1) a prestroke history of hypertension and (2) APOE4 were more cognitively impaired at 3 months after stroke. METHODS A total of 257 participants were genotyped and outcomes from ...

The reminiscence bump is the tendency to recall relatively many personal events from the period in which the individual was between 10 and 30 years old. This effect has only been found in autobiographical memory studies that used participants who were older than 40 years of age. The increased recall of recent events possibly obscures the reminiscence bump in the results of younger participants....

Embodiment has highlighted the importance of sensory-motor components in cognition. Perception and memory are thus very tightly bound together, and episodic and semantic memories should rely on the same grounded memory traces. Reduced perception should then directly reduce the ability to encode and retrieve an episodic memory, as in normal aging. Multimodal integration deficits, as in Alzheimer...

INTRODUCTION We report previously unpublished, early pilot studies performed with a brain-health food supplement containing a proprietary blend of 100 mg phosphatidylserine (PS) and 80 mg phosphatidic acid (PA) produced from soy lecithin. METHODS Serum analysis after single PS+PA ingestion was performed in healthy volunteers. A 3-month double-blind, placebo-controlled study assessed the influ...

Reminiscence plays an important role in the lives of older adults [8]. Many perfect the art of storytelling and enjoy its social benefits. The telling of stories of past events and experiences defines family identities and is an integral part of most cultures. Losing the ability to recollect past memories is not only disadvantageous, but can prove quite detrimental, especially to many older adu...

The brain's ability to alter its functional and structural architecture in response to experience and learning has been extensively studied. Mental stimulation might serve as a reserve mechanism in brain aging, but macrostructural brain changes in response to cognitive training have been demonstrated in young participants only. We examined the short-term effects of an intensive memory training ...