Staining reactions characteristic of collagen and reticulin are found in pathologically altered glomeruli (1, 2), and fibrils with the periodicity of collagen fibrils have been observed occasionally in electron micrographs of severely damaged glomerular tufts. However, as far as we are aware, fibrils have not been found by light or electron microscopy in the normal glomerular tuft, except at th...

In this study we aimed to set up an in vitro culture of the rabbit amnion in order to support in vivo fetal membrane healing capacity following fetoscopy. Fetal membranes were collected from a mid-gestational rabbit, and cultured on collagen support material for 14 days. 34 rabbits at 22-23 days gestational age (GA) underwent fetoscopy. The entry site was randomly allocated to 4 closure techniq...

Background/Aim. Type IV collagen belongs to the group of nonfibrillar collagens and is an important component basement membranes, where it accounts for approximately 50% its structural elements. The aim study was describe expression distribution type in embryonic fetal metanephric kidney determine volume density tissue each trimester development. Methods. material consisted 19 human embryos/fet...

Observations regarding the repair of wounds (i.e., wound healing) date to physicians in ancient Egypt and battle surgeons in classic Greece. The liver’s ability to regenerate forms the basis of the Greek myth involving Prometheus. The clotting of blood to prevent exsanguination was recognized as the first necessary event in wound healing. At the time of the American Civil War, the development o...

The role of extracellular matrix in the regulation of epithelial cell surface polarity development was studied using MDCK cells. Previous work has demonstrated that MDCK cells cultured in suspension form epithelial cysts having polarized cell surface distributions of several membrane proteins. When MDCK suspension cysts are incubated within collagen gel, a dynamic epithelial membrane remodeling...

BACKGROUND The role of tumour inflammation and the dysplastic epithelial-stromal interactions on the nature of collagen fibres in the extracellular matrix of dysplastic epithelium is not fully understood. The present study was aimed to evaluate and compare the inflammation and pathological stromal collagen (loosely packed thin disorganized collagen) present in mild, moderate and severe epitheli...

OBJECTIVE The operating procedure of a resternotomy in open-heart surgery is a complicated procedure with potentially problematic outcomes partly due to potential adhesions in the pericardial cavity and retrosternal space. Use of a collagen membrane has shown encouraging results in adhesion prevention in several regions of the body. This study was designed to evaluate the effectiveness of the u...

Nonwoven fabric with cellulosic base has many Features ability to absorb biological fluids and can easily adapt for different types locations of wounds, which made it common unique in surgical dressing. The study aimed To design samples one layer two layers nonwoven fabrics the inner deep endoscopic wound dressings control fluid leakage. 100% cotton, viscose, viscose/polyester (70:30) % were us...

BACKGROUND Nicotine can pass through placental blood barrier and accumulate in the developing organs of fetus. Also, entering the breast milk, nicotine can have an effect on the neonates. Investigations have showed that collagen IV is one of the most important micro vessels basement membrane components. OBJECTIVE In this study, the effect of maternal nicotine exposure in pre and postnatal per...