The objective of this review is to examine whether a redundant colon gives rise to symptoms like constipation and volvulus. In 1820, Monterossi made drawings of colons with displacements and elongation of the colon found during autopsy. In 1912, Kienböeck first visualized a redundant colon using bismuth, and Lardennois and Auborg named the anatomic variant dolichocolon in 1914. The criteria wer...

BACKGROUND & AIMS Gastrointestinal motility is regulated by enteric neural circuitry that includes enteric neurons and glia. Enteric glia monitor synaptic activity and exhibit responses to neurotransmitters that are encoded by intracellular calcium (Ca2+) signaling. What role evoked glial responses play in the neural regulation of gut motility is unknown. We tested how evoking Ca2+ signaling in...

Acupuncture is useful for functional bowel diseases, such as constipation and diarrhea. However, the mechanisms of beneficial effects of acupuncture on colonic function have scarcely ever been investigated. We tested the hypothesis that electroacupuncture (EA) at ST-36 stimulates colonic motility and transit via a parasympathetic pathway in conscious rats. Hook-shaped needles were inserted at b...

Ageing is associated with an increased incidence of constipation in humans. The contribution that the ageing process makes to this condition is unclear. The aim of this study was to determine the effects of age on faecal output and colonic motility in male C57BL/6J mice and to determine the role that altered tachykinin signalling plays in this process. Total faecal output recorded over a 24h pe...

Gottlob, (1993, in \Proceedings, 34th IEEE Symp. on Found. Comput. Sci.," pp. 42{ 51), showed that any set recognized by polynomial-size, log-depth trees with queries to SAT is p tt-reducible to NP. Based on his technique, it is shown for any set A and any k 1, that NC k (A) AC k?1 (R NP ctt (A)), where R NP ctt (A) is the NP ctt-closure of A. As a consequence, it is shown for any class C that ...

BACKGROUND/AIMS Opioid induced bowel dysfunction (OIBD) is associated with decreased gastrointestinal (GI) propulsive activity due to intake of opioid analgesics. DA-9701, a novel prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber has promising effects on GI motor function. Therefore, we aim to evaluate the prokinetic effects of DA-9701 in an OIBD model of guinea pig. METHOD...

introduction: hydronephrosis is one of the major causes of referring infants for nuclear medicine investigation. renal dynamic study is the most reliable investigation for such children. however direct evaluation of renogram leads to generation of parameters that have no physiological interpretation. the configuration of renogram is very much dependent upon the rate at which radiopharmaceutical...