This article defines a new minimization problem, the k-Compartment Problem, and presents its solution. The k-Compartment Problem is to determine the minimum sum of k + 1 line segments that intersect two parallel lines which form k compartments.

Previously, we proposed a new paradigm to explain the compartment-specific role of autophagy in tumor metabolism. In this model, autophagy and mitochondrial dysfunction in the tumor stroma promotes cellular catabolism, which results in the production of recycled nutrients. These chemical building blocks and high-energy "fuels" would then drive the anabolic growth of tumors, via autophagy resist...

Acute renal failure frequently occurs in the intensive care unit as a primary or secondary event in association with trauma, surgery, or comorbid medical disease. An increasingly common thread linking surgical and medical disease management is the abdominal compartment syndrome. In particular, the rise of early goal-directed therapy for the initial resuscitation and management of severe sepsis ...

The perinucleolar compartment (PNC) is a subnuclear body characterized by its location to the periphery of the nucleolus. The PNC is a dynamic structure and is highly enriched in RNA-binding proteins and pol III RNA. The structural stability of the PNC is dependent on continuous pol III transcription and the presence of key proteins. The PNC is associated with malignancy both in vitro and in vi...

A case of atraumatic gluteal compartment syndrome complicated by sciatic nerve palsy and acute rhabdomyolysis is presented. A presumed diagnosis of deep venous thrombosis led to a delay in diagnosis. Gluteal compartment syndrome should be considered in the differential diagnosis of the swollen leg.

Multiplexed positron emission tomography (PET) imaging provides perfectly registered simultaneous functional and molecular of more than one biomarker. However, the separation multiplexed PET signals within a single scan is challenging due to fact that all tracers emit positrons, which, after annihilating with nearby electron, give rise 511 keV photon pairs are detected in coincidence. Compartme...

BACKGROUND There are few reports concerning chronic compartment syndrome producing symptoms in the forearm, although in the lower limb this is a well recognised condition. The objective was to demonstrate that chronic compartment syndrome is a cause of exercise induced forearm pain and transient upper limb dysfunction and that forearm compartment decompression can reliably relieve the associate...

Intra-abdominal hypertension (IAH) associated with organ dysfunction defines the abdominal compartment syndrome (ACS). Elevated intra-abdominal pressure (IAP) adversely impacts pulmonary, cardiovascular, renal, splanchnic, musculoskeletal/integumentary, and central nervous system physiology. The combination of IAH and disordered physiology results in a clinical syndrome with significant morbidi...

A young man presented with a painful and swollen thigh, without any history of trauma, illness, coagulopathic medication or recent exertional exercise. Preliminary imaging delineated a haematoma in the anterior thigh, without any fractures or muscle trauma. Emergent fasciotomies were performed. No pathology could be identified intra-operatively, or on follow-up imaging. A review of thigh compar...