In the present study, we investigated the effect of a new anticancer Pd(II) complex, 1,10-phenanthroline-n-butyl dithiocarbamato Pd(II) nitrate, on the heme releasing from human hemoglobin (Hb) as well as alterations in the structure and function of Hb using different spectroscopic methods of UV-Vis, fluorescence and circular dichroism (CD)at two temperatures of 25 and 37 °C. Fluorescence data ...

Living organisms can sense and respond to external and internal stimuli. Response isdemonstrated in many forms including modulation of gene expression profiles, motility,secretion, cell death, etc. Nevertheless, all forms share a basic property: they depend on sensingsmall changes in the concentration of an effector molecule or subtle conformational changes ina protein and invoking the appropri...

Mutations in the ergosterol biosynthesis gene 11 (ERG11) of Candida albicans have been frequently reported in fluconazole-resistant clinical isolates. Exploring the mutations and their effect could provide new insights into the underlying mechanism of fluconazole resistance.  Erg11p_Threonine285Alanine (Erg11p_THR285ALA), Erg11p_Leucine321Phenylalanine (Erg11p_LEU321PHE) and Erg11p_Serine457Pro...

background: cerebrovascular disease leading to stroke is the most common cause of aphasia. speakers with agrammatic non-fluent aphasia have difficulties in production of movement-derived sentences such as passive sentences, topicalized constituents, and wh-questions. to assess the production of complex sentences, some passive, topicalized and focused sentences were designed for patients with no...

secure electronic transaction (set) protocol is an open protocol, which has the potential to emerge as a powerful tool in securing of electronic transactions. the quality of a design of an ecommerce protocols has a great influence on achieving non-functional requirements (nfrs) to the system. an increasingly important non-functional attribute of complex software systems is adaptability. softwar...

the application of the [pd{c6h3(ch2ch2nh2)-4-ome-5-κ2-c,n}(μ-br)]2 complex of 2-methoxyphenethylamine in the heck coupling reaction was considered under both conventional and microwave irradiation conditions, and their results were compared. this complex is an efficient, stable and non-sensitive to air and moisture catalyst for the vinylation of substituted aryl halides with different electroni...

Introduction: Alzheimer disease (AD) is the most common form of dementia worldwide. The modalities to diagnose AD are generally expensive and limited. Both the central nervous system (CNS) and the retina are derived from the cranial neural crest; therefore, changes in retinal layers may reflect changes in the CNS tissue. Optical coherence tomography (OCT) machine can show delicate retinal layer...

introduction multiple dentigerous cysts are rare and mostly associated with syndromes. case presentation the present case report is unique, as the dentigerous cysts enclosed the lateral incisor, canine, first and second premolars of the mandible and were accompanied by a complex odontoma, instead of first mandibular molar. conclusions multiple unilateral nosyndromic dentigerous cysts with compl...