A multi item inventory model with demand dependent on unit price and leading time with limited storage space and set up cost is considered in this paper. The varying production and leading time crashing costs are considered to be continuous functions of unit price and leading time respectively. The model is solved using Karush Kuhn Tucker conditions approach with optimal order quantity, unit pr...

OBJECTIVE To determine the willingness to pay (WTP) and the benefit-cost of modern contraceptives delivered through the public sector in Nigeria. METHODS Data were collected from 4517 randomly selected households. The WTP for the 6 major contraceptive methods available in the public sector was elicited. Logistic regression was used to determine whether the decision to state a positive WTP amo...

We revisit the issue of multiplicity of equilibria when monetary policy is conducted with either the interest rate or the money supply as the sole instrument of policy. We show that in standard monetary models there are interest rate feedback rules, and also money supply rules, that implement a unique global equilibrium. This is a contribution to a literature that either concentrates on conditi...

Liver disease and thromboembolism are the most frequent and severe side effects associated with the use of clotting-factor concentrates in haemophiliacs. Knowledge and careful evaluation of the risk factors related to their development appear to be the most reasonable policy for prevention. themolysis due to significant isoantibody infusion and bleeding associated to abnormal platelet function ...

The polymerase chain reaction (PCR) was used to detect hepatitis C (HCV) viral sequences (HCV-RNA) in clotting factor concentrates that had been stored at 4 degrees C for 1 to 16 years. A total of 43 concentrates were tested, comprising 31 batches of factor VIII, 6 of factor IX, 2 of antithrombin III, 3 of FEIBA, and 1 of factor VII. HCV-RNA was detected in 13 of the 43 batches (30.2%). Concent...

Factor IX concentrates were evaluated for their factor VII content and for the presence of activated factor VII through use of a coupled amidolytic assay insensitive to activated factor VII and a clotting assay sensitive to activated factor VII. The factor VII content of the concentrates studied (except for one concentrate purposely produced to exclude factor VII) varied between 33 and 621 U/vi...