نتایج جستجو برای: concurrent chemoradiotherapy

تعداد نتایج: 69532  

Journal: :Anticancer research 2015
Kana Kimura Yoshiyuki Itoh Tohru Okada Rie Nakahara Mariko Kawamura Seiji Kubota Junji Itoh Mariko Hiramatsu Yasushi Fujimoto Takashi Shibata Shinji Naganawa

AIM To improve the outcomes of radiotherapy alone for T2 glottic carcinoma (GC), we initiated a prospective study of concurrent chemoradiotherapy with S-1 for patients with early GC, primarily T2 cases. We report the efficacy and safety of this protocol. PATIENTS AND METHODS Eligible patients had T1b or T2 glottic squamous cell carcinomas. Patients received S-1 (55.3 mg/m(2)/day, once daily) ...

2017
Shinnosuke Takemoto Yoichi Nakamura Minoru Fukuda Hiroaki Senju Hiroshi Gyotoku Hirokazu Taniguchi Midori Shimada Takaya Ikeda Hiroyuki Yamaguchi Katsumi Nakatomi Nobuyuki Hayashi Hiroshi Soda Hiroshi Mukae

BACKGROUND Chemoradiotherapy is the standard treatment for locally advanced non-small cell lung cancer (NSCLC); however, it is disputed whether this treatment is suitable for patients aged ≥75. This study was conducted to determine the maximum tolerated dose (MTD) of pemetrexed for use in concurrent radiotherapy for elderly patients with locally advanced non-squamous NSCLC. METHODS The eligib...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2012
Wei-Hong Wei Xiu-Yu Cai Tao Xu Guo-Yi Zhang Yong-Feng Wu Wei-Neng Feng Li Lin Yan-Ming Deng Qiu-Xia Lu Zhe-Li Huang

BACKGROUND AND PURPOSE Cisplatin is the most common chemotherapeutic agent for loco-regionally advanced nasopharyngeal carcinoma (NPC); however, toxicity is a limiting factor for some patients. We retrospectively compared the efficacy and toxicity of weekly docetaxel-based and cisplatin-based concurrent chemoradiotherapy in loco-regionally advanced NPC. METHODS AND MATERIALS Eighty-four patie...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Hamid Saeidi Saedi Fariborz Mansour-Ghanaei Farahnaz Joukar Afshin Shafaghi Soodabeh Shahidsales Zahra Atrkar-Roushan

BACKGROUND Survival rates after resection of advanced gastric cancer are extremely poor. An increasing number of patients with gastric carcinomas (GC) are therefore being treated with preoperative chemotherapy. We evaluated 36 month survival rate of GC patients that were treated by adding a neoadjuvant chemoradiotherapy before gastrostomy. MATERIALS AND METHODS Patients with stage II or III g...

2014
MENG SU LUCHENG ZHU WENHUA LUO HANGPING WEI CHANGLIN ZOU

Primary anorectal (PA) malignant melanoma (MM) is a rare disease associated with a high mortality rate. The most appropriate treatment strategy for PAMM remains controversial. A 55-year-old female patient, who was misdiagnosed with locally advanced rectal carcinoma, was treated with preoperative radiotherapy and concurrent oral capecitabine. During the therapy, grade 1 leukopenia occurred, howe...

2017
Michael J. Baine Timothy Dorius Nathan Bennion Lynette Smith Weining Zhen Apar Kishor Ganti

Objectives Concurrent chemoradiotherapy is standard of care in locally advanced oropharyngeal cancer (LA-OPC). This treatment regimen results in significant acute toxicities. This study investigates the effect of treatment-related toxicity on patient outcomes. Methods Patient information was retrospectively collected for patients treated for LA-OPC between 2007 and 2014. Factors analyzed incl...

2011
Oscar Arrieta Cynthia Villarreal-Garza Jesús Zamora Mónika Blake-Cerda María D de la Mata Diego G Zavala Saé Muñiz-Hernández Jaime de la Garza

BACKGROUND Brain metastases occur in 30-50% of Non-small cell lung cancer (NSCLC) patients and confer a worse prognosis and quality of life. These patients are usually treated with Whole-brain radiotherapy (WBRT) followed by systemic therapy. Few studies have evaluated the role of chemoradiotherapy to the primary tumor after WBRT as definitive treatment in the management of these patients. ME...

Journal: :Anticancer research 2013
Naoyoshi Onoda Shinichiro Kashiwagi Satoru Noda Hidemi Kawajiri Tsutomu Takashima Tetsuro Ishikawa Kosei Hirakawa

BACKGROUND Although rare, treatment of anaplastic thyroid carcinoma (ATC) is very difficult due to its aggressiveness and resistance to therapeutic efforts. PATIENTS AND METHODS We reviewed outcomes for six patients who underwent a unique chemoradiotherapy regimen consisting of external irradiation (45 to 60 Gy) combined with concurrent low-dose weekly docetaxel administration at 10 mg/m(2). ...

2017
Vivek Verma Charles B. Simone Maria Werner-Wasik

For patients with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC), concurrent chemoradiotherapy improves overall survival as compared to sequential chemotherapy and radiation therapy, but is associated with higher rates of toxicities. Acute, clinically significant esophagitis or pneumonitis can occur in one in five patients. The risks of esophagitis and pneumonitis can impac...

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