In randomized clinical trials where the effects of post-randomization factors are of interest, the standard regression analyses are biased due to unmeasured confounding. The instrumental variables (IV; Angrist et al., 1996) and G-estimation procedures under structural nested mean models (SNMMs; Robins, 1994) allow one to make valid inference even if unmeasured confounding is present. Two IV app...

Introduction: This study aimed to investigate sleep architecture in patients with primary snoring and obstructive sleep apnea. Methods: In this study, we analyzed polysomnographic data of 391 clients who referred to Sleep Disorders Research Center (SDRS). These people were classified into three groups based on their Apnea-Hypopnea Index (AHI) and snoring; control, Primary Snoring (PS), and Obs...

Potato is an important food crop with high water-use-efficiency but low drought tolerance. The bottleneck in tolerance breeding phenotyping managed field environments. Fundamental research on predominantly done container-based test systems controlled However, the portability of results from these to performance under conditions debated. Thus, we analyzed effects climate conditions, container si...

bedsore is a very important problem in bedridden patients. it affects patients’ lives and imposes substantial costs to society. its incidence approaches 38% and its annual prevalence is estimated to be 14.8% in patients who are admitted in hospitals. the national pressure ulcer advisory panel (npuap) and the european pressure ulcer advisory panel (epuap) define bedsore as “a localized injury to...

background: statins have been effective medications in lowering serum total cholesterol (tc) concentrations across populations over time. the aim of this study was to estimate national and provincial trends in atorvastatin sales in iran, to systematically quantify its relationship with socio-economic indicators, and changes in tc level.   methods : in this retrospective ecological study, conduc...