نتایج جستجو برای: congenital cmv
تعداد نتایج: 127723 فیلتر نتایج به سال:
Arecent review made note of the 50th anniversary of the identification of human cytomegalovirus (CMV) in cell culture, an important milestone that paved the way to today’s understanding of the molecular biology, immunology, and clinical importance of this ubiquitous viral infection. In the past 50 years, much progress has been made in the characterization of disease caused by CMV. Solid organ a...
Cytomegalovirus (CMV) is the leading cause of viral-associated congenital infections. Moreover, it can also be acquired. Between 50 to 80 percent world’s population seropositive for CMV and most clinical disease occurs in individuals previously infected with CMV. Rarely, serious infection has occurred healthy immune system. In contrast immunocompetent patients, higher morbidity mortality end or...
OBJECTIVE We evaluated the neuropsychological outcome of children with proven congenital cytomegalovirus (CMV) infection and normal consecutive fetal neurosonographic examinations. METHODS We retrospectively reviewed laboratory and imaging findings of children with congenital CMV infection. The study group consisted of children with a positive polymerase chain reaction (PCR) in amniotic fluid...
Newborns in the United States and in many other developed countries are routinely tested for inherited metabolic disease using blood samples collected in hospital nurseries. Drops of newborn blood, typically collected from a heel stick, are blotted within circles marked on filter paper. These dried blood spots (DBSs) are submitted to central laboratories for testing. Although the diagnosis of c...
The mechanisms of inhibition of cytomegalovirus (CMV) infection by human CD13 (aminopeptidase N)-specific antibodies were studied. These antibodies protect CD13-negative and -positive cells from CMV infection only if incubated with the virus inoculum, suggesting they bind to CMV virions. The association of a CD13-like molecule with virions was further supported by the transfer of CD13 immunorea...
BACKGROUND Congenital infection with human cytomegalovirus (CMV) is a major cause of morbidity and mortality. In an uncontrolled study published in 2005, administration of CMV-specific hyperimmune globulin to pregnant women with primary CMV infection significantly reduced the rate of intrauterine transmission, from 40% to 16%. METHODS We evaluated the efficacy of hyperimmune globulin in a pha...
Human cytomegalovirus (CMV) is a member of the herpesviridae family. It is a double stranded, enveloped and ubiquitous DNA virus that rarely causes disease in healthy individuals yet can cause serious diseases in the fetus and in immunosuppressed individuals [1]. Most CMV infections are inapparent, but the virus can cause a wide range of diseases in susceptible individuals. Fetal CMV infection ...
BACKGROUND The relationship between gestational age at time of maternal cytomegalovirus (CMV) infection and outcome of fetal infection is not well defined because the timing of maternal infection is usually not known. OBJECTIVE To determine whether congenital cytomegalovirus (CMV) infection following primary maternal infection during the first trimester of pregnancy is more likely to lead to ...
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