BACKGROUND The teratogenic effects of immunomodulatory and certain antimicrobial therapies are described in small rodents and humans. While the described teratogenic effects in small rodents have been extrapolated to make conclusions about its use in the pregnant dam, teratogenic effects of prednisone and doxycycline have not yet been reported in the dog. Here we report and describe midline def...

Amniotic Band Syndrome is a sporadic congenital disorder that may result in constriction bands, amputation and multiple craniofacial, visceral and body wall defects. Its incidence is estimated at approximately 1:5000 to 1:10,000 pregnancies. Band formation most frequently affects the distal segments, including the hand. We report a case of constriction amniotic bands involving the trunk.

Congenital defects of the pericardium are considered rare. Until 1979 , the reported cases were only about 200.1 Total absence of the left pericardium is the most common defect2 and less common is a partial defect of the left pericardium. Other types, i.e. isolated right-sided defects, total pericardial absence and diaphragmatic pericardial defects are very rare.3 Before the last decade, t...

Objective: to identify types of birth defects in HIV vertically exposed children and to determine the rate of congenital disorders counted in children born to HIV infected mothers. We analyzed the data recorded for HIV perinatally exposed children followed up in the National Institute for Infectious Diseases “Prof. Dr. Matei Balş”, Bucharest, the Pediatric Department from January 1 2006 to Dece...