Background Rickets is the most common non-communicable disease in pediatrics developing countries, often observed societies with strict vegetarian diets and not introduced to foods enriched vitamin D. This poses a barrier effective treatment, making it chronic subclinical disease. Objective: study aims assess prevalence of rickets among Saudi children infants Arar, Arabia, identify risk factors...

Objective: To compare the duration for stabilization of respiratory rate in children having pneumonia with and without rickets. Methods: This case control study was conducted at Department of Paediatrics Dow University of Health Sciences and Civil Hospital Karachi, Pakistan, from January to August 2016. In this study 100 diagnosed cases of pneumonia with age group of >2 months to 60 months were...

There is a paucity of published data on the types of paediatric orthopaedic conditions that require surgery and factors influencing their outcome in most parts of Sub-Saharan Africa. This is a necessary audit to improve paediatric orthopaedic practice. We carried out an audit of all elective orthopaedic operations performed in children at Awolowo University Teaching Hospitals Complex in Ile-Ife...

It is interesting to note the way in which medical knowledge has developed over the years with regard to diseases superficially akin to classical rickets. The first stage followed as a result of the disappearance, owing to the improved knowledge of nutrition, of classical rickets as a common source of bony deformity. This led to the clearer recognition of the remaining 'resistant' forms of rick...

Vitamin D deficiency rickets is the most significant manifestation of vitamin D deficiency in growing children. Concerns have been raised in New Zealand (NZ), and worldwide, that cases continue to present, and may be possibly increasing. We undertook a prospective study to investigate the incidence and characteristics of vitamin D deficiency rickets in NZ children. Prospective surveillance of V...

It is interesting to note the way in which medical knowledge has developed over the years with regard to diseases superficially akin to classical rickets. The first stage followed as a result of the disappearance, owing to the improved knowledge of nutrition, of classical rickets as a common source of bony deformity. This led to the clearer recognition of the remaining 'resistant' forms of rick...

We present the case of a preterm 6-month-old African American infant who developed craniosynostosis secondary to rickets. This child developed rickets and macrocephaly by the age of 6 months. His head continued to enlarge, and a 3D CT obtained when the child was 2 years old revealed metopic and bilateral coronal craniosynostosis. This CT suggested increased intracranial pressure, and therefore,...

The prevalence of clinical vitamin D deficiency (rickets and osteomalacia) is high in many parts of the world, and there is a resurgence of rickets among children of ethnic minority groups in Europe and Australasia. Plasma 25-hydroxyvitamin D concentration (25OHD) is a useful risk marker of clinical vitamin D deficiency. This review summarizes the factors that contribute to differences in 25OHD...

Vitamin D deficient rickets is prevalent in Turkey and a considerable number of children are at risk of growth retardation, impaired bone formation and fracture. In order to check whether vitamin D receptor (VDR) gene polymorphism relates to the vitamin D deficient rickets, we analyzed VDR gene FokI, TaqI and ApaI polymorphisms in 24 Turkish vitamin D deficient rickets patients and 100 healthy ...

The levels of type X collagen in mineralizing normal chicken epiphyses and nonmineralizing rachitic chicken tibial epiphyses were measured and compared. Qualitative immunoperoxidase studies with anti-chick type X collagen monoclonal antibodies on sections from normal and rachitic cartilage demonstrated that the type X collagen levels in rachitic growth plates are reduced. Northern hybridization...