The device consists of four parts (Fig 1). The disposable mouthpiece (Inspiron No. 001200) fits into one end of a 6inch corrugated tube (Hudson Corr-A-Tube II, No. 1410). The other end of this tube is coupled to a connector (BardParker oxygen hose connector No. 5002) via a 22 X 22-mm adapter (Bard-Parker No. 5095). This connector fits snugly onto the male hub of the rubber tubing of most commer...

Complex genetic networks consist of structural modules that determine the levels and timing of a cellular response. While the functional properties of the regulatory architectures that make up these modules have been extensively studied, the evolutionary history of regulatory architectures has remained largely unexplored. Here, we investigate the transition between direct and indirect regulator...

Reo is a coordination model based on circuit-like connectors which coordinate components through the interplay of data flow, synchronisation and mutual exclusion, state, and context-dependent behaviour. This paper proposes a scheme based on connector colouring for determining the behaviour of a Reo connector by resolving its context dependent synchronisation and mutual exclusion constraints. Co...

DNA packaging in the bacteriophage phi29 involves a molecular motor with protein and RNA components, including interactions between the viral connector protein and molecules of pRNA, both of which form multimeric complexes. Data are presented to demonstrate the higher order assembly of pRNA together with the affinity of pRNA:pRNA and pRNA:connector interactions, which are used to propose a mode...

The aim of this paper is to show how the generic approach to connector architectures, presented in the first part of this work, can be applied to a given modeling formalism to define architectural component and connector notions associated to that formalism. Starting with a review of the generic approach, in this second part of the paper we consider two modeling formalisms: elementary Petri net...

Aortic intramural haematoma is similar to classic aortic dissection, which causes a life-threatening medical condition, and immediate diagnosis and treatment are crucial. The optimal therapy for intramural haematoma of the abdominal aorta remains controversial. Conservative medical management is usually the first choice of treatment for uncomplicated cases. Surgical intervention is usually requ...

The harsh operating environment of the automotive application makes the semi-permanent connector susceptible to intermittent high contact resistance which eventually leads to failure. Fretting corrosion is often the cause of these failures. However, laboratory testing of sample contact materials produce results that do not correlate with commercially tested connectors. A multicontact (M-C) reli...