Consanguineous marriages have been practiced since the early existence of modern humans. Until now consanguinity is widely practiced in several global communities with variable rates depending on religion, culture, and geography. Arab populations have a long tradition of consanguinity due to socio-cultural factors. Many Arab countries display some of the highest rates of consanguineous marriage...

background it seems that there is a relationship between consanguinity and profound hearing loss but there is little data about the association of consanguinity and hearing loss in iran. objectives the aim of this study is to demonstrate the causes of profound bilateral sensorineural hearing loss among iranian samples who are candidates for cochlear implantation. methods this study was retrospe...

BACKGROUND AND AIMS Chronic nonspecific multiple ulcer of the small intestine is a recently proposed enteropathy characterized by persistent blood and protein loss from the small-bowel. We examined possible segregation of the disease in family pedigrees. METHODS All cases of the disease diagnosed at our institution were reviewed with respect to particular focuses on the presence of close cons...

Genetic counseling is the process in which an individual or a family obtains information and advice about a genetic condition that may affect the individual, his progeny, his relatives, or the family as a whole. Based on this knowledge, he can take the pertinent decision regarding marriage, reproduction, abortion and health management. Genetic counseling includes five themes, medical management...

Inherited neurodegenerative disorders are common in the Kingdom of Saudi Arabia as a result of the high rate of consanguinity. This is a complex field with a multitude of different disorders characterized by a variety of clinical manifestations, complex molecular biology, and a long list of potential investigations. As a result, this is often a confusing and difficult area for non-specialists, ...

Abstract Background Consanguineous marriage is widely practised across the world. Its effect on acute lymphoblastic leukaemia (ALL) controversial as both parents share some of genes which might increase incidence sharing recessive genes. However, other theories suggest that consanguinity have a protective factor it does for types cancers. This study aims to childhood ALL and consanguinity. Meth...

Etemadi K1, Khazaii MR2 1. MSC of Human Genetic, Molecular Medicine and Genetic department, Medical school, Hamadan University of medical sciences. 2. Assistant professor of Pediatric Urology Abstract Background: The Bardet Biedl syndrome is a heterogenous and autosomal recessive disorder. Primary features are: retinitis pigmentosa, obesity, polydactyly, mental retardation, renal abnorm...